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2018, Number 2

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Rev Med MD 2018; 9.10 (2)

Prevalence of upper gastrointestinal symptoms in patients with diabetes mellitus and associated factors

Sánchez-Maza YDJ, Meixueiro-Daza A, García-Zermeño KR, Remes-Troche JM

Language: Spanish
References: 15
Page: 100-105
PDF size: 608.11 Kb.


ABSTRACT

Introduction. Up to 76% of patients who present for consultation for diabetes mellitus (DM) have reported having one or more gastrointestinal symptoms, while 50-55% of patients report having upper gastrointestinal symptoms. The autonomic neuropathy explains to a large extent the disorders of digestive motility in these subjects, however, it is possible that other factors are involved. Our objective was to determine the prevalence and relationship between gastrointestinal symptoms in patients with diabetes mellitus and its associated factors.
Material and Methods. a prospective, cross-sectional and comparative study, in which the PAGI SYM questionnaires (validated in Spanish) were applied to subjects with type 2 diabetes mellitus that presented to two reference centers in 2013. Descriptive statistics and SPSS V. 22 were used.
Results. 157 subjects were included (69.4% women), with an average age of 55.8 years. The average time of evolution of the DM was 10.9 ± 9.1 years and the average glycosylated hemoglobin (HbA1c) was 13.5 ± 31.5. The most common complication was diabetic neuropathy with 27.40%. 83.4% of the patients had at least one upper GI symptom. The presence of the most common GI symptoms according to the PAGI SYM were: heartburn in 38.9%, postprandial fullness with 38.2% and 31.8% nocturnal heartburn. The overall presence of symptoms compatible with gastroparesis was 71%.
Discussion. More than 80% of patients with type 2 DM have at least one GI symptom, the most frequent being symptoms associated with gastroparesis. The factors associated with the presence of GI symptoms were glycemic control and the presence of neuropathy and retinopathy.


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