Rocha RJL, Villanueva SE, Martínez HMP, Sierra ME, Soto QR, Pérez AJ, Blanco LE

Language: Spanish
References: 14
Page: 430-433
PDF size: 65.51 Kb.

ABSTRACT

Objective: Report for first time in Mexico a case of hereditary mixed polyposis and review the literature. Background: The hereditary mixed polyposis syndrome (HMPS) is an uncommon condition, distinguished by presence of a different histological pattern of polyps in digestive tract, clinically manifested by diarrhea, anemia and weight loss. Case report: Male patient, 38 years old, with familiar antecedent (dead sister) with polyps and gastric cancer. With history of a 1 year with bleeding and mucous diarrhea, and weight loss of a 28.6 pounds. Pale at physical examination, without abdominal signs. At blood test with hemoglobin of 9.7 g/dL, and colonoscopy with multiple polyps within colon and rectum, upper endoscopy with a big esophageal polyp and multiple polyps in gastric and duodenal lining smaller than 1 cm. Contrast study of intestine was normal. Histopathologic study of the polyps report mixed pattern of polyps: (hyperplasic-adenomatous, juvenile-adenomatous, adenoma-inflammatory-hyperplasic, hyperplasic-adenomatous with a high degree dysplasia); juvenile in esophagus, and hyperplasic in stomach and duodenum. Patient was undergone to total proctocolectomy and reconstruction by “J” ileoanal pouch with good outcome, and endoscopic esophageal polypectomy, with actual surveillance.

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