2004, Number 1
<< Back Next >>
Rev Mex Cardiol 2004; 15 (1)
Carotid stenting in patients of high risk: Current follow-up to long term
Palacios RJM, Bazzoni RA, Torres HM, Comparán NA et al
Language: Spanish
References: 31
Page: 5-13
PDF size: 152.90 Kb.
ABSTRACT
Objective: The cerebral vascular accident is the 3rd cause of death and first in permanent inability in the industrialized countries. In this small study
we demonstrate the security, effectiveness so much initial as long term of the Carotid Stenting (SC) in patient of high risk.
Methods: Of Feb 98 to
Jun 03 we treated 46 pts (51 lesions) with carotid stenosis (F:17, M 29), 5 pts with bilateral stenosis, an half age of 67.3 + 8.9 years, 55% payees
of arterial Hypertension, 42% Diabetics, 48% smoke +, and 86.9% of ischemic cardiopathy; 24% with previous myocardial infarction (MI), a Fraction of expulsion of LV 46.2 + 16%; 84% was symptomatic and 21% had antecedents of previous Stroke with minimum neurological sequels, in 43% of the group(20 pts) we carry out a combined revascularization.
Result: The stenosis
average before CS was of 79.6 + 9.8% and later 6.36 + 6.27%, the Diameter minimum luminar was incremented of 1.52 + 0.5 at 6.04 + 1.47 mm, in the last 32 pts (69.5%) we use filter of protection carotidea being obtained macroscopic material in 26 of them (81%). The success angiography and Clinical of the procedure it was obtained in 100 and 98% respectively
Complications: Two events neurological noipsilateral, one resolved without sequels to the 7
days, the other one culminates in secondary cerebral hemorrhage to crisis hipertensiva and anticoagulation excess with partial recovery to the 60 days, 1 pts present renal insufficiency, we didn’t obtain neurological ipsilaterales complications or deaths periprocedures. To a current follow-up of 21.7 + 19.55 (r = 1-63 months) 2 pts died one to 6 months
and another to 3.5 years search-procedure in both cases documented by MI; 34 pts (74%) they were evaluated in the clinical Doppler being reported restenosis in 4 pts, being only demonstrated by angiography
quantitative restenosis in 1 pts (2%), in none of the 44 alive pts with current follow-up in external consultation have presented events neurological ipsilaterales, all continue with antiplatelet treatment
and a very strict control of factors of Risk.
Conclusion: The benefit in these patients was also demonstrated in the SAPPHIRE trial that included of high risk pts and the final points of death/Stroke/MI to 30 days in pts randomized to CS vs Endarterectomy was (5.8% vs 12.6% p = 0.047 respectively). there is not doubt that the angioplasty with CS with endoprotection is a safe and effective procedure, of minimum risk even in considered of high risk pts, with long term certain benefits.
REFERENCES
American Heart Association. Heart and Stroke Statistical Update. Dallas, Tx. American Heart Association; 1998.
Timsit SG, Sacco RL, Mohr JP, Foulkes MA, Tatemichi TK, Wolf PA et al. Early clinical differentiation of cerebral infarction from severe atherosclerosis and cardioembolism. Stroke 1992; 23: 486-91.
North American Symptomatic Carotid Endarterectomy Trial collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl Med 1991; 325: 445-453.
European Carotid Surgery Trialist´s Collaborative Group. MRC European Carotid Surgery Trial. Interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid Stenosis. Lancet 1991; 337: 1235-43.
Asymptomatic Carotid Atherosclerosis study. Clinical advisory. Carotid endarterectomy for patients with asymptomatic internal carotid artery stenosis. Stroke 1994; 25: 2523-2524.
Diethrich EB, Ndiaye M, Reid DB. Stenting in the carotid artery: initial experience in 100 patient. J Endovascular Surg 1996; 3: 42-62.
Yadav JS, Roubin GS, Iyers S. Elective stenting of the extracraneal carotid arteries: immediate and late outcome. Circulation 1997; 95: 376-381.
Roubin GS, Yadav JS, Iyer SS et al. Carotid stent-supported angioplasty: a neurovascular intervention to prevent stroke. Am J Cardiol 1996; 78(Suppl. 3A): 8-12.
Donnan GA, Davis SM, Chambers BR, Gates PC. Surgery for prevention of stroke. Lancet 1998; 351: 1372-1373.
Antiplatelet Trialist´s collaboration: Collaborative overview of randomized trials of antiplatelet treatment, I: Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients. B Med J 1994; 308: 81-106.
Gent B, Blakely JA, Easton JD et al. The Canadian American Ticlopidine Study (CATS) in Thromboembolic stroke. Lancet 1989; 1: 1215-1220.
Anonymous. Collaborative overview of randomized trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists’ Collaboration. Br Med J 1994; 308: 81-106.
Ringleb PA, Bhatt DL, Hirsch AT, Topol EJ, Hacke W, for the CAPRIE Investigators: Benefit of Clopidogrel Over Aspirin Is Amplified in Patients With a History of Ischemic Events. Stroke 2004; 35: 528-532.
Roeder GO, Langlois YE, Jager KA et al. The natural history of carotid arterial disease in asymptomatic patients with cervical bruits. Stroke 1984; 15: 605-613.
Autret A, Pourcelot L, Saudeau D. et al. Stroke risk in patients with carotid stenosis. Lancet 1987; 1: 888-890.
Dennis M, Bamford J, Sandercock P et al. Prognosis of transient ischemic attacks in the Oxfordshire Community Stroke Project. Stroke 1990: 848-853.
Sacco RL, Wolf PA, Kannel WB et al. Survival and recurrence following stroke. The Framingham study. Stroke 1982; 13: 290-295.
Barnett HJM. Final results of the North American Symptomatic Endarterectomy Trial (NASCET): 23rd Joint Conference on Stroke and Cerebral Circulation. Stroke Council of the American Heart Association. Orlando FL. February 1988.
Moore WS, Barnett HJM, Beebe HG et al. Guideline for carotid endarterectomy: a multidisciplinary consensus statement from the Ad Hoc Committee. American Heart Association. Stroke 1995; 26: 188-201.
Winslow et al. The appropriateness of carotid endarterectomy. N Engl J Med 1988; 318: 721-727.
Goldstein LE, Badels C, Davis JN. Interrater reliability of the NIH stroke scale. Arch Neurol 1989; 46: 660-662.
Yadav JS, Roubin GS, Iyer S, Vitek J, King P, Jordan WD, Fisher WS. Elective Stenting of the extracranial Arteries. Circulation 1997; 95: 376-381.
Yadav JS, Roubin GS, King P, Iyer S, Vitek J. Angioplasty and Stenting for Restenosis After Carotid Endarterectomy. Stroke 1996; 27: 2075-2079.
Dorros G. Stent-supported Carotid Angioplasty; Should It Be Done, and, If So, by Whom? A 1998 Perspective. Circulation 1998; 98: 927-930.
Bettmann MA, Katzen BT, Cochairs JW, Brant-Zawadzki M, Broderick JP et al. Carotid Stenting and Angioplasty: A Statement for Healthcare Professionals From the Councils on Cardiovascular Radiology, Stroke, Cardio-Thoracic and Vascular Surgery, Epidemiology and Prevention, and Clinical Cardiology. American Heart Association. Stroke 1998; 29: 336-338.
Mackey WC, O’Donnell TF, Callow AD. Carotid endarterectomy contralateral to an occluded carotid artery: Perioperative risk and late results. J Vasc Surg 1990; 11: 778-85.
Perler BA. The impact of advanced age on the results of carotid endarterectomy in the elderly. Is it worthwhile? Surgery 1994; 116: 479-83.
Reul GC, Cooley DA, Duncan JM et al. The effect of coronary bypass on the outcome of peripheral vascular operations in 1,093 patients. J Vasc Surg 1986; 3: 788-98.
Vermeulen FE, Hamerlijnck RP, Defauw JJ, Ernst SM. Synchronous operation for ischemic cardiac and cerebrovascular disease: early results and long-term follow-up. Ann Thorac Surg 1992; 53: 381-9.
Yadav JS. Stenting and Angioplasty With Protection in Patients at High Risk for Endarterectomy: The SAPPHIRE Study. American Heart Association Late Breaking Clinical Trials (abstract). Circulation 2002; 106: 9.
Shawl F, Kadro W, Domanski MJ et al. Safety and efficacy of elective carotid artery stenting in high-risk patients. J Am Coll Cardiol 2000; 35: 1721-1728.