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2013, Number 3

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Rev Cubana Farm 2013; 47 (3)

Development and evaluation of tablets from spray dried extract of yerba mate (Ilex paraguariensis St. Hil A)

Roman J, Garcia CV, Loureiro MAS, Barcellos SFE

Language: English
References: 27
Page: 379-388
PDF size: 197.81 Kb.


ABSTRACT

Introduction: yerba mate (Ilex paraguariensis St. Hil A) is a South American plant species of Aquifoliaceae family. The presence of methylxanhtines and clorogenic acids was reported in this species. These compounds have antioxidant activity and could be included in tablets, a pharmaceutical form presently unavailable in the market.
Objective: to develop tablets containing yerba mate spray dried extract.
Methods: the tablets were produced by direct compression with yerba mate dried extract. The dried extract was evaluated for yield, repose angle, compressibility index, residual moisture and caffeine content. The tablets were evaluated in the following parameters: external appearance, weight, hardness, friability, disintegration and caffeine content.
Results: the tablets complied with the general pharmacopoeial specifications.
Conclusions: this method is effective to produce tablets containing spray dried extract from yerba mate.


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