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ISSN 1561-2988 (Impreso)

2013, Número 3

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Rev Cubana Farm 2013; 47 (3)


Desarrollo y evaluación de las tabletas de extracto seco por aspersión de yerba mate (Ilex paraguariensis St. Hil A)

Roman J, Garcia CV, Loureiro MAS, Barcellos SFE

Idioma: Ingles.
Referencias bibliográficas: 27
Paginas: 379-388
Archivo PDF: 197.81 Kb.


RESUMEN

Introducción: la yerba mate (Ilex paraguariensis St. Hil A) es una planta de América del Sur, de la familia Aquifoliaceae. Para esta especie se informó la presencia de ácidos clorogénico y metilxantinas. Estos compuestos tienen actividad antioxidante y podría incluirse en tabletas, una forma farmacéutica que no está disponible.
Objetivo: desarrollar comprimidos que contienen extracto seco por aspersión de yerba mate.
Métodos: se produjeron comprimidos por compresión directa. Se determinaron al extracto seco los parámetros de rendimiento, ángulo de reposo, índice de compresibilidad, humedad y contenido de cafeína, y a los comprimidos, apariencia externa, peso, dureza, friabilidad, desintegración y contenido de cafeína.
Resultados: los comprimidos cumplieron con las especificaciones generales planteadas en farmacopeas.
Conclusión: el método empleado es eficaz en la producción de comprimidos que contienen extracto seco de yerba mate.


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