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2012, Number 2

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Med Sur 2012; 19 (2)

Acute liver failure. Current concepts

Carrillo-Esper R, León-Valdivieso JY

Language: Spanish
References: 49
Page: 76-87
PDF size: 551.28 Kb.


ABSTRACT

Acute liver failure (ALF) is a catastrophic multiorgan syndrome occurring in previously healthy individuals that is characterized by severe hepatocellular dysfunction. The cause varies geographically and socioeconomically. Hepatitis viruses are the most common cause in the developing world; whereas drug induced ALF predominates in the United States and Europe. The clinical syndrome is the same, regardless of the cause. It has a unique combination of rapidly progressive, severe multiple organ failure, unpredictable and often devastating complications. Improved medical management and emergent orthotopic liver transplantation have improved overall patient survival.


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