Identifying risk factors for pancreatitis. Post-endoscopic retrograde cholangiopancreatography. A prospective study

Jesús Ocádiz Carrasco; Luis Gabriel Alfaro Fattel; Ruth Alicia Gutiérrez Padilla; Ricardo Blas Azotla

2012, Number 2

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Rev Mex Cir Endoscop 2012; 13 (2)

Identifying risk factors for pancreatitis. Post-endoscopic retrograde cholangiopancreatography. A prospective study

Ocádiz CJ, Alfaro FLG, Gutiérrez PRA, Blas AR

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Language: Spanish
References: 19
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ABSTRACT

Background: Acute pancreatitis is the most important complication of endoscopic cholangiopancreatography (ECP), with reported incidence around 5%. Risk factors identified to the date may be classified as patient or operator related. Main objective was to know the incidence of post ECP pancreatitis and the main risk factors associated to this procedure in our institution. Methods: Prospective analysis was made on 86 patients who underwent ECP during January 2010 to January 2011 at Endoscopy Department in the Nuevo Sanatorio Durango. Clinical evaluation and serum levels of amylase and lipase were performed 24 hours after the procedure in order to define the presence of acute mild or severe pancreatitis and identifying the main variables. Results: The most common indication for ECP was choledocholithiasis (65%), incidence of pancreatitis was 6.9% (six cases) and the main risk factors were age below 60 (RR: 2.17, CI: 0.27 to 17.64), poor diagnosis and suspicion of choledocholithiasis and the lack of confirmation after the procedure (RR: 41.00, CI: 10.43 to 161.18) along with the difficult Vater ampulla cannulation (RR: 8.4, CI: 1.65 to 42.69). Conclusion: ECP must not be considered an innocuous diagnostic procedure. Patients with major risk factors for developing pancreatitis in our study were those with no justified indication for the procedure.

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