2004, Number 4
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An Med Asoc Med Hosp ABC 2004; 49 (4)
Dexmedetomidine versus midazolam as pre-anesthesia medication for endoscopic paranasal sinuses surgery. Haemodynamic stability assessment
Martínez TR, Zambada C, Álvarez GR, González VM, Yáñez C, Reyes E, Díaz A, Domínguez B
Language: Spanish
References: 11
Page: 184-190
PDF size: 55.17 Kb.
ABSTRACT
One of the main targets of pre-anesthesia medication is to relief anxiety of the patient who will be taken to a surgical procedure. The drug mainly used to aim this goal is midazolam, but this is not the only one which produces this effect. Another group of drugs which produces the same effect is the alpha 2 adrenergic receptors like dexmedetomidine which has anothers hemodynamical effects like a decrease in heart rate and arterial blood pressure. We take advantage of these effects to medicate patients whom were programmed for and endoscopic paranasal sinuses surgery during which, the infiltration with lidocaine with epinephrine increases both heart rate and blood pressure. We formed 2 groups with 20 patients each, one of the groups receiving dexmedetomidine as premedication and another group receiving midazolam. We assumed that patients receiving dexmedetomidine will not increase the heart rate or the blood pressure as much as the midazolam group. We found evidence that sustain our hypothesis and no adverse effects were found.
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