2011, Number 4
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Perinatol Reprod Hum 2011; 25 (4)
Dysmorphic craniofacial features due to prenatal cocaine and alcohol exposure
Salinas-Torres VM, Serra-Ruiz L, Cadena-González PJ, Angulo-Castellanos E
Language: Spanish
References: 14
Page: 224-229
PDF size: 135.32 Kb.
ABSTRACT
Introduction: Cocaine and alcohol are potentially teratogenic in human embryo development, craniofacial dysmorphic features in children with cocaine and alcohol embryopathy are well defined and the effects of both could be seen together in a prenatally exposed individual to these harmful substances.
Case report: Mother of 33 years old with history of alcohol and cocaine consumption, during the last six years and all the gestational period (corroborated by self report and urinalysis). Male, newborn obtained via vaginal delivery at 35 weeks, because premature rupture of membranes. On the third day of life begun with rejection of oral feeding and irritability, during a period of 24 hours. Clinical examination found craneofacial dysmorphia, but other systems and organs were normal. The cocaine toxicological report in the urinalysis, was positive in the first 24 hours.
Conclusions: We describe a case with craniofacial features consistent with prenatal cocaine and alcohol exposure. It is controversial whether the dysmorphic craniofacial features described were the product of independent or combined action of both teratogenic or just a coincidental finding. Further detailed observation and proper investigation is required in such cases in order to acquire more precise knowledge of which these pathologies are produced.
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