Soto-de la Fuente AE, Aguilar-Loya M, Méndez-Vargas MM, Zamudio-Martínez P, López-Rojas P, Salinas-Tovar S, Marín-Cotoñieto IA

Language: Spanish
References: 27
Page: 565-572
PDF size: 140.07 Kb.

ABSTRACT

Objective: to identify the association between industrial bronchitis and exposure to hydroalcohol.
Methods: in a prospective study, 80 workers exposed to hydroalcohol answered a standardized questionnaire and had two spirometry tests based on the American Thorax Society (ATS) criteria, to evaluate functional capacity and predominant spirometric patterns. The test included the parameters: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), the ratio FEV1/FVC, the peak expiratory flow (PEF), the forced expiratory flow 25-50 (FEF50) and the forced expiratory flow 25-75% (FEF 25%-75%). Fisher exact test was used to identify differences. An environmental sampling of hydro-alcohols was done as well.
Results: 85% of workers were women and 15% men, with respiratory symptoms as follows: 25% with cough and expectoration, 14% thoracic pressure feeling, 23% dyspnea; 36% eye, nose or throat irritation. The spirometry results were: 25% for pulmonary normal pattern; 66% had obstructive pattern; 3% had restrictive patterns and 6% mix pattern. 25% of workers with obstructive pattern and 10% of normal pattern had symptoms. It was obtained an OR = 1.9 (95% CI = 1.135-3.195; p = 0.021) for the time of exposure to hydroalcohols and the presence of industrial bronchitis. The monitoring of hydro-alcohols reported: 131.1 mg/m3 for isopropyl alcohol and 438.3 mg/m3; 49 workers (61%) had bronchitis symptoms and 58 (72%) showed obstructive or mixed patterns in the spirometry tests. The exposure to hydro-alcohols was below the limits established by the Mexican Official Norm.

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