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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2011, Number 2

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An Med Asoc Med Hosp ABC 2011; 56 (2)

Analgesic efficacy of morphine versus parecoxib in postoperative laparoscopic cholecystectomy patients

Ramírez VA, Delgado CMM, Camacho MJP

Language: Spanish
References: 10
Page: 73-78
PDF size: 60.57 Kb.


ABSTRACT

Background: Laparoscopic cholecystectomy has been adopted as the treatment of choice for cholelithiasis; if we adjoin it with effective pain management it is associated with increased patient satisfaction. We compared the analgesic efficacy of morphine and parecoxib and determined the frequency of adverse effects. Material and Methods: In a prospective, comparative, longitudinal study, randomized trial of 32 patients undergoing laparoscopic cholecystectomy were divided into 2 groups, Group A received morphine at 0.10 mg/kg and the Group B parecoxib 40 mg. Postoperative pain was assessed using visual analog scale and adverse effects at 30, 60 and 120 minutes from the end of drug administration. Rescue dose was administered in patients with EVA greater than or equal to 5. Results: The need for rescue analgesia at 30 minutes was 81.3% in group A, compared with 18.8% in group B (p ‹ 0.05). At 60 minutes group A was 25% and 0% for group B (p ‹ 0.05). After 120 minutes no additional analgesia was required. Conclusions: Parecoxib showed greater analgesic efficacy in patients undergoing laparoscopic cholecystectomy than morphine.


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