2008, Number 3
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Rev Mex Anest 2008; 31 (3)
Comparative study of tramadol versus placebo in knee surgery under regional anesthesia
Paz-Estrada C, Fuentes PM
Language: Spanish
References: 20
Page: 179-183
PDF size: 54.14 Kb.
ABSTRACT
Objective: To evaluate the analgesic effect of the hydrochlorate of tramadol epidural compared with placebo in the postoperative of patients programmed for knee surgery.
Material and methods: we was carried out a controlled clinical rehearsal, blind double, in the hospital «Guillermo Luis Fernández Hernández-Baquero», Holguín, Cuba, during the months of february to august of the 2006; 84 patients were selected, which were divided at random in two groups of 42 patients each one; we apply anesthesia lumbar epidural and catheter was placed. The agent anesthetic employee went mepivacaine to 2% 5 mg/kg. We was administered by the catheter: Group I: tramadol 100 mg dissolved in 10 mL of solution saline physiologic 0.9% and Group II: solution saline physiologic 0.9%. It was valued heart frequency and tension arterial half transoperative and postoperative. The evaluation of the pain was carried out with Similar Visual Scale. The mensurations were carried out in three occasions: recovery, at the 2 and 4 hours of the postoperative one. They registered the most frequent secondary effects.
Results: The evaluation at the 4 hours of the postoperative one reported slight pain in the group placebo: 16%; moderate pain with tramadol in 21% and in the placebo 67% of the cases (p ‹ 0.05); 23.8% only presented severe pain in the group placebo. The opposing adverse effects were in the Group I nauseas and vomits in a 31 and 21%, respectively.
Conclusions: The analgesia epidural with tramadol prolongs the anesthetic time with good analgesic quality.
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