Cárdenas LLE, Herrera EJJ, Mora LG, Ortega CL, Pérez TH, Berlanga RF, Moreno GA, Mijares GJM

Language: Spanish
References: 26
Page: 143-151
PDF size: 69.82 Kb.

ABSTRACT

Objective: To assess the usefulness of endoscopic sphincterotomy in the treatment of acute pancreatitis in terms of morbidity, mortality, hospital stay, and recurrence.
Design: Study of cases and controls.
Setting: Third level health care hospital.
Method: Retrospective review of the clinical histories of patients with severe or mild biliary pancreatitis, with or without retrograde endoscopic cholangiopancreatography (RECP) and endoscopic sphincterotomy (ES). Independent variables were: age, gender, APACHE II and Ranson scores, time elapsed between admittance and RECP with ES. Dependent variables were: major complications, mortality, duration of hospital stay, recurrence. Descriptive statistics was used, odds ratio (OR) was calculated at confidence intervals of 95% (CI 95%).
Results: Global analysis showed that RECP with ES did not modify frequencies of morbidity, mortality, hospital stay duration, and recurrence of pancreatitis. In acute pancreatitis, patients from the control group depicted higher APACHE II scores at admittance and at 48 hours (p = 0.033 and 0.008, respectively). However, RECP with ES did not decrease morbidity and mortality due to pancreatitis, independently from the time elapsed between admittance and the procedure. OR calculation did not reveal that RECP with ES constitutes a factor improving the prognosis of patients with biliary pancreatitis.
Conclusion: In this study, RECP with ES did not decrease morbidity, mortality, hospital stay duration, and recurrence in patients with acute pancreatitis, independently from the severity of the disease.

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