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Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2024, Number S1

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Rev Latin Infect Pediatr 2024; 37 (S1)

Consensus of the Mexican Association of Paediatric Infectious Diseases: prevention of respiratory syncytial virus infection in Mexico, 2024

Ortiz IFJ, González SN, Arias GE, Castillo BJI, Gutiérrez TIF, Laris GA, Lima RMV, Martínez ML, Moreno ES, Ochoa PU, Ordoñez OJ, Ortiz CB, Revelo CO, Tamez RO, Tena AG, Vázquez RM, Villa GM, Otero MF

Language: Spanish
References: 98
Page: s6-28
PDF size: 502.18 Kb.


ABSTRACT

Introduction: Respiratory Syncytial Virus (RSV) infections are among the leading causes of morbidity and mortality in children under two years of age and adults over 65. Therefore, this consensus aims to analyze, discuss, and provide recommendations on the benefits and impact of immunoprophylaxis in reducing the burden of RSV-related respiratory diseases in Mexico and Latin America. Material and methods: using the academic consensus model, we compiled and critically reviewed the available scientific literature on current and controversial topics related to RSV. We adhered to the guidelines set forth in (outlined in?) the "Guidelines for the Development of Consensus" and the European AGREE initiative, focusing on critical reading and evaluation criteria. The recommendations generated are presented according to the GRADE scale. The consensus involved multidisciplinary teams comprising neonatologists, obstetricians, and pediatric infectious disease specialists affiliated with the Mexican Association of Pediatric Infectology (AMIP). The studies and manuscripts reviewed were selected based on keywords such as "respiratory syncytial virus", "vaccine", "monoclonal antibodies", "epidemiology", "vaccine safety and efficacy", and "vaccine compliance", utilizing databases including PubMed, Google Scholar, EMBASE, Cochrane, and virtual libraries from Oxford, Harvard, and Tecnológico de Monterrey. Priority was given to articles published between January 2019 and August 2024, with older references included for context or when they represented the most robust information available. The consensus process involved one in-person meeting, two virtual sessions, and (an?) external review by three independent experts. Results: eleven relevant and/or controversial topics were identified and critically analyzed according to the evidence found. The results of the critical review of the selected articles were presented with their corresponding GRADE recommendation level.


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