Castro-López DX, Rivas-Vega AD, Peña-Cuellar AJ, Ortega-Torres M, Castro-Gamboa S, Torres-Bugarín O

Language: Spanish
References: 15
Page: s16-22
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ABSTRACT

Diabetes mellitus type 1 (DM1) is a pancreatic beta autoimmune disease with increased blood glucose studied since the first century, this has encouraged biotechnology to introduce alternative therapeutic measures to exogenous insulin for chronic and poorly controlled patients with DM1; an example of these is pancreas transplantation, which has multiple varieties of presentation, among them are allotransplants, artificial and computerized pancreases. Pancreatic allotransplants are the most studied group, whose objective is to potentiate 1% of salvageable islets from a donor, compared to the second group, which are bioartificial pancreases that produce a new pancreas thanks to pluripotential cells. These two groups have similarities both in cells used and culture patterns and differences in transplant location and tissue viability. On the other hand, computerized pancreases are characterized by the use of algorithms for glucose monitoring; although these techniques have been studied, biomaterial technology has not yet been catalyzed as a medical reality, however, it is becoming.

REFERENCES

1. Sánchez Rivero G. Historia de la diabetes. Gac Med Bol. 2007;30(2):74-78.

2. Akolpoglu MB, Inceoglu Y, Bozuyuk U, Sousa AR, Oliveira MB, Mano JF, et al. Recent advances in the design of implantable insulin secreting heterocellular islet organoids. Biomaterials. 2021;269:120627. doi: 10.1016/j.biomaterials.2020.120627.

3. Berney T, Wassmer CH, Lebreton F, Bellofatto K, Fonseca LM, Bignard J, et al. From islet of Langerhans transplantation to the bioartificial pancreas. Presse Med. 2022;51(4):104139. doi: 10.1016/j.lpm.2022.104139.

4. Bhattacharjee A, Easwaran A, Leow MK, Cho N. Design of an online-tuned model based compound controller for a fully automated artificial pancreas. Med Biol Eng Comput. 2019;57(7):1437-1449. doi: 10.1007/s11517-019-01972-5.

5. Krentz NAJ, Shea LD, Huising MO, Shaw JAM. Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering. Lancet Diabetes Endocrinol. 2021;9(10):708-724. doi: 10.1016/S2213-8587(21)00170-4.

6. Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL et al. Engineering a clinically translatable bioartificial pancreas to treat type I diabetes. Trends Biotechnol. 2018;36(4):445-456. doi: 10.1016/j.tibtech.2018.01.007.

7. Citro A, Moser PT, Dugnani E, Rajab TK, Ren X, Evangelista-Leite D, et al. Biofabrication of a vascularized islet organ for type 1 diabetes. Biomaterials. 2019;199:40-51. doi: 10.1016/j.biomaterials.2019.01.035.

8. Smood B, Bottino R, Hara H, Cooper DKC. Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article. Int J Surg. 2019;69:100-107. doi: 10.1016/j.ijsu.2019.07.032.

9. Soetedjo AAP, Lee JM, Lau HH, Goh GL, An J, Koh Y, et al. Tissue engineering and 3D printing of bioartificial pancreas for regenerative medicine in diabetes. Trends Endocrinol Metab. 2021;32(8):609-622. doi: 10.1016/j.tem.2021.05.007.

10. Photiadis SJ, Gologorsky RC, Sarode D. The current status of bioartificial pancreas devices. ASAIO J. 2021;67(4):370-381. doi: 10.1097/MAT.0000000000001252.

11. Crisóstomo J, Araújo F, Granja P, Barrias C, Sarmento B, Seica R. Increasing levels of insulin secretion in bioartificial pancreas technology: co-encapsulation of beta cells and nanoparticles containing GLP-1 in alginate hydrogels. Health Technol. 2020;10:885-890. doi: 10.1007/s12553-020-00427-4.

12. Opara A, Canning P, Alwan A, Opara EC. Challenges and perspectives for future considerations in the bioengineering of a bioartificial pancreas. Ann Biomed Eng. 2023. doi: 10.1007/s10439-023-03180-7.

13. Mouré A, Bekir S, Bacou E, Pruvost Q, Haurogné K, Allard M, De Beaurepaire L, et al. Optimization of an O2-balanced bioartificial pancreas for type 1 diabetes using statistical design of experiment. Sci Rep. 2022;12(1):4681. doi: 10.1038/s41598-022-07887-w.

14. Takahashi Y, Sekine K, Kin T, Takebe T, Taniguchi H. Self-condensation culture enables vascularization of tissue fragments for efficient therapeutic transplantation. Cell Rep. 2018;23(6):1620-1629. doi: 10.1016/j.celrep.2018.03.123.

15. Skrzypek K, Barrera YB, Groth T, Stamatialis D. Endothelial and beta cell composite aggregates for improved function of a bioartificial pancreas encapsulation device. Int J Artif Organs. 2018;41(3):152-159. doi: 10.1177/0391398817752295.