medigraphic.com
ISSN 2007-932X (Digital)
Órgano Oficial de Difusión de la Comisión Nacional de Arbitraje Médico

2020, Número 2

<< Anterior Siguiente >>

Rev CONAMED 2020; 25 (2)


Eritrocitosis y miomatosis

Delgado TFV

Idioma: Español
Referencias bibliográficas: 22
Paginas: 84-88
Archivo PDF: 137.75 Kb.


RESUMEN

Los leiomiomas uterinos son tumores asociados a tumores de eritrocitosis secundaria. En la literatura se ha propuesto y demostrado la producción de eritropoyetina ectópica por fibromas de músculos lisos. Se ha demostrado que la eritrocitosis aislada es el resultado de la producción ectópica de eritropoyetina (Epo) en varias neoplasias malignas que incluyen células renales y carcinoma hepatocelular. Se ha encontrado que ocurre en tumores extraños como el hemangioblastoma cerebeloso y los adenomas. Se le asocia con menos frecuencia a leiomioma uterino. Los cirujanos emplean cada vez más la laparoscopia para la histerectomía. Sin embargo, el papel de la laparoscopia en presencia de un útero gigante todavía es debatible. En pacientes con síndrome miomatoso eritrocitario (SME) presente con signos y síntomas atribuidos a una masa abdominopélvica o eritrocitosis la flebotomía preoperatoria ayuda a disminuir la gravedad de la eritrocitosis y se ha utilizado para mitigar el riesgo de complicaciones trombóticas. La resección quirúrgica del leiomioma es un enfoque válido para el tratamiento de SME.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. de Guzman GS, Manalo EM. Myomatous erythrocytosis syndrome: a case series. Case reports women’s heal [Internet]. 2019; 24: e00139. Available from: https://doi.org/10.1016/j.crwh.2019.e00139.

  2. Mui J, Yang MM, Cohen T, McDonald DI, Hunt H. More than a myoma: a review of myomatous erythrocytosis syndrome. J Obstet Gynaecol Canada [Internet]. 2020; 42 (2): 198-203.e3. Available from: https://doi.org/10.1016/j.jogc.2018.12.025.

  3. Gordon B, Fischbeck T, Salamo R, Schroff S. Treating myomatous erythrocytosis syndrome with uterine artery embolization. Obstet Gynecol. 2019; 133 (6): 1274-1277.

  4. Macciò A, Chiappe G, Lavra F, Sanna E, Nieddu R, Madeddu C. Laparoscopic hysterectomy as optimal approach for 5400 grams uterus with associated polycythemia: a case report. World J Clin Cases. 2019; 7 (19): 3027-3032.

  5. Tanos V, Berry KE. Benign and malignant pathology of the uterus. Best Pract Res Clin Obstet Gynaecol [Internet]. 2018; 46: 12-30. Available from: https://doi.org/10.1016/j.bpobgyn.2017.10.004.

  6. Marchioli R; CYTO-PV Collaborative Group. Cardiovascular events and intensity of treatment in polycythemia vera. N Engl J Med. 2013; 368: 22-33.

  7. Asano R, Asai-Sato M, Miyagi Y, Mizushima T, Koyama-Sato M, Nagashima Y et al. Aberrant expression of erythropoietin in uterine leiomyoma: implications in tumor growth. Am J Obstet Gynecol. 2015; 213: 199.e1-8.

  8. Bulman JC, Ascher SM, Spies JB. Current concepts in uterine fibroid embolization. Radiographics. 2012; 32: 1735-1750.

  9. Gordeuk VR, Key NS, Prchal JT. Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis. Haematologica. 2019; 104: 653-658 [PMID: 30872370 doi: 10.3324/haematol.2018.210732].

  10. Moulder JK, Siedhoff MT, Till SR, Moll S. Management considerations for patients with uterine fibroids and concurrent venous thromboembolism. Curr Opin Obstet Gynecol. 2016; 28: 329-335 [PMID: 27253238 doi: 10.1097/GCO.0000000000000286].

  11. Lacharite-Roberge AS, Raza F, Bashir R, Dass CA, Moser GW, Auger WR, Toyoda Y, Forfia PR, Vaidya A. Case series of seven women with uterine fibroids associated with venous thromboembolism and chronic thromboembolic disease. Pulm Circ. 2019; 9: 2045894018803873 [PMID: 30204062 doi: 10.1177/2045894018803873].

  12. Hunt BJ. Hemostasis at Extremes of Body Weight. Semin Thromb Hemost 2018; 44: 632-639 [PMID: 29986373 doi: 10.1055/s-0038-1661385].

  13. Huber FL, Latshang TD, Goede JS, Bloch KE. Does venous blood gas analysis provide accurate estimates of hemoglobin oxygen affinity? Ann Hematol. 2013; 92: 517-521. [PMID: 23307600 doi: 10.1007/s00277-012-1667-z].

  14. McMullin MFF, Mead AJ, Ali S, Cargo C, Chen F, Ewing J et al. A guideline for the management of specific situations in polycythaemia vera and secondary erythrocytosis: a british society for haematology guideline. Br J Haematol. 2019; 184: 161-175 [PMID: 30426472 doi: 10.1111/bjh.15647].

  15. Macciò A, Kotsonis P, Lavra F, Chiappe G, Sanna D, Zamboni F et al. Laparoscopic removal of a very large uterus weighting 5320 g is feasible and safe: a case report. BMC Surg. 2017; 17: 50 [PMID: 28472966 doi: 10.1186/s12893-017-0248-4].

  16. Macciò A, Chiappe G, Kotsonis P, Nieddu R, Lavra F, Serra M et al. Surgical outcome and complications of total laparoscopic hysterectomy for very large myomatous uteri in relation to uterine weight: a prospective study in a continuous series of 461 procedures. Arch Gynecol Obstet. 2016; 294: 525-531. [PMID: 27016346 DOI: 10.1007/s00404-016-4075-0].

  17. Wright JD, Herzog TJ, Tsui J, Ananth CV, Lewin SN, Lu YS et al. Nationwide trends in the performance of inpatient hysterectomy in the United States. Obstet Gynecol. 2013; 122: 233-241. [PMID: 23969789 doi: 10.1097/AOG.0b013e318299a6cf].

  18. Stewart EA, Cookson CL, Gandolfo RA, Schulze‐Rath R. Epidemiology of uterine fibroids: a systematic review. BJOG Int. J. Obstet Gynaecol. 2017; 124 (10): 1501-1512. doi: 10.1111/1471-0528.14640. https://pubmed.ncbi.nlm.nih.gov/28296146/

  19. Tanos V, Berry KE. Benign and malignant pathology of the uterus. Best Pract Res Clin Obstet. 2018; 46: 12-30.

  20. Singh SS, Belland L. Contemporary management of uterine fibroids: focus on emerging medical treatments. Curr Med Res Opin. 2015; 31 (1): 1-2.

  21. Ono Y, Hidaka T, Fukuta K, Kouchi K, Yasoshima K, Takagawa K et al. A case of myomatous erythrocytosis syndrome associated with a large uterine leiomyoma. Case Rep Obstet Gynecol. 2014; Available at: https://doi.org/10.1155/2014/602139. (https://www.researchgate.net/publication/260255111_A_Case_of_Myomatous_Erythrocytosis_Syndrome_Associated_with_a_Large_Uterine_Leiomyoma).

  22. Qu H, Li Z, Zhai Z, Liu C, Wang S, Guo S et al. Predicting of venous thromboembolism for patients undergoing gynecological surgery. Medicine (Baltimore). 2015; 94: e1653 [PMID: 26426660 doi: 10.1097/MD.0000000000001653].




2020     |     www.medigraphic.com