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Órgano oficial de la Facultad de Odontología, UNAM

2019, Número 3

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Rev Odont Mex 2019; 23 (3)


Mecanismos inflamatorios en la destrucción periodontal

Solís-Suárez DL, Pérez-Martínez IO, García-Hernández AL

Idioma: Español
Referencias bibliográficas: 55
Paginas: 159-172
Archivo PDF: 518.83 Kb.


RESUMEN

La enfermedad periodontal se inicia por la presencia de bacterias. Sin embargo, la inflamación es la principal causa de su cronicidad y la destrucción de los tejidos periodontales, principalmente del hueso alveolar que conduce al edentulismo. Los mecanismos que llevan a la destrucción de los tejidos incluyen el incremento no regulado de mediadores inflamatorios y alteraciones en los mecanismos de resolución de la inflamación. El carácter silencioso e indoloro de la patología ocasiona que el padecimiento sea ignorado permitiendo su evolución a cuadros crónicos y severos, por lo que su incidencia es alta. La presente revisión describe los mecanismos moleculares y celulares de la inflamación durante el progreso de la EP, así como su participación en la destrucción de los tejidos de soporte. El conocimiento de la patogénesis de la EP con base en la inflamación crónica podría brindar opciones terapéuticas novedosas para la reducción de la EP y sus repercusiones.


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