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TIP Revista Especializada en Ciencias Químico-Biológicas

2012, Número 2

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TIP Rev Esp Cienc Quim Biol 2012; 15 (2)


Estructura y función de la ATP sintasa de las arqueas aeróbicas

Miranda-Astudillo HV

Idioma: Español
Referencias bibliográficas: 88
Paginas: 104-115
Archivo PDF: 486.14 Kb.


RESUMEN

Desde el descubrimiento de las arqueas ha llamado la atención su capacidad para sobrevivir en ambientes difíciles. A través de los ańos, las arqueas han pasado de ser rarezas extremófilas a ser consideradas organismos de importancia universal que han sido utilizados para elucidar preguntas biológicas fundamentales. La filogenia del dominio Arquea se encuentra en constante cambio y cuenta hasta la fecha con 5 ramas principales: Crenarchaeota, Euryarchaeota, Thaumarchaeota, Korarchaeota y Nanoarchaeota. En el presente trabajo se enlistan las principales características estructurales de los complejos respiratorios de los géneros de arqueas aeróbicas más estudiados. Se presenta una comparación morfológica de la ATP sintasa de estos organismos con el resto de la familia de las ATPasas rotatorias (F- y V-ATPasas); así como un análisis topológico de este complejo enzimático (A1Ao-ATP sintasa) tomando como base la función de cada una de las subunidades que lo conforman.


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