2021, Número 3
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Rev Educ Bioquimica 2021; 40 (3)
TOR (Target of Rapamycin): Emperador en la toma de decisiones que regula el crecimiento y desarrollo de las plantas
Salazar DK, Tzvetanka DD
Idioma: Español
Referencias bibliográficas: 44
Paginas: 100-110
Archivo PDF: 484.26 Kb.
RESUMEN
La señalización por la vía de Target Of Rapamycin (TOR) es esencial en la integración
de estímulos ambientales, disponibilidad de nutrientes y energía con el control por
factores de crecimiento, señales de desarrollo y diferenciación en organismos eucariontes.
En las plantas, su descubrimiento y caracterización son más recientes y
se ha estudiado poco en especies relevantes agronómicamente. Específicamente, se
describió una vía similar a la del complejo TORC1 de mamíferos pero con particularidades
del linaje vegetal que involucran la respuesta a fitohormonas y a la luz,
la adaptación a estrés y el control del ciclo de vida de la planta. TOR tiene un gran
impacto en el perfil metabólico, la proliferación/diferenciación celular y la regulación
de la expresión genética en respuesta a glucosa, auxinas y estrés. Aquí se describen
los componentes principales de la vía TOR en la planta modelo Arabidopsis, la señalización
río arriba de TOR, los procesos que regula y algunos de los hallazgos que la
presentan como un blanco atractivo para el mejoramiento de cultivos.
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