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Instituto Nacional de Salud Pública

2021, Number 3

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salud publica mex 2021; 63 (3)

Nutritional status of iron, vitamin B12, vitamin A and anemia in Mexican children: results from the Ensanut 2018-19

De la Cruz-Góngora V, Martinez-Tapia B, Shamah-Levy T, Villalpando S

Language: English
References: 34
Page: 359-370
PDF size: 346.74 Kb.


ABSTRACT

Objective. To describe the current status of micronutrient deficiencies (MD) and anemia in Mexican children. Materials and methods. Serum data from 1 382 pre-school-age children (1-4 years) and 3 590 school-age children (5-11 years) Ensanut 2018-19 participants were analyzed. Iron deficiency (ID), vitamin B12 deficiency (B12D), vitamin A depletion (VADp), and anemia were identified. Logistic regression models were used to identify associations between sociodemographic characteristics of children and MD. Results. Anemia was present in 28.9 and 19.2% of the children aged 1-4 and 5-11, respectively; in ID 10 and 5.1%; B12D, in 5.1 and 4.8%, and VADp, in 4.7 and 4.3%. 18.5% of the preschool-age children and 13% of the school-age children had at least one MD associated to anemia. Conclusions. MD and anemia affect the younger children in larger proportion. Fortification and supplementation programs should be reinforced to avoid the long-term consequences of MD.


REFERENCES

  1. International Food Policy Research Institute. Global Hunger Index. The Challenge of Hidden Hunger. Bonn/Washington,D.C./Dublin: Concern Worldwide/Welthungerhilfe, 2014 [cited August, 2020]. Available from: https://www.ifpri.org/sites/default/files/ghi/2014/feature_1818.html

  2. Villalpando S, García-Guerra A, Ramírez-Silva CI, Mejía-Rodríguez F, Matute G, Shamah-Levy T, et al. Estado de hierro, zinc y yodo en niños menores de 12 años y en mujeres de 12-49 años de edad en México: una encuesta probabilística nacional. Salud Publica Mex. 2003;45(suppl 4):S520- 9. Available from: https://saludpublica.mx/index.php/spm/article/view/4664

  3. Villalpando S, De la Cruz V, Shamah-Levy T, Rebollar R, Contreras-Manzano A. Nutritional status of iron, vitamin B12, folate, retinol and anemia in children 1 to 11 years old . Results of the Ensanut 2012. Salud Publica Mex. 2015;57(5):372-84. https://doi.org/10.21149/spm.v57i5.7616

  4. De La Cruz-Góngora V, Villalpando S, Mundo-Rosas V, Shamah-Levy T. Prevalencia de anemia en niños y adolescentes mexicanos: Comparativo de tres encuestas nacionales. Salud Publica Mex. 2013;55(suppl 2):180-9. Available from: https://saludpublica.mx/index.php/spm/article/view/5114

  5. De la Cruz-Góngora V, Villalpando S, Shamah-Levy T. Prevalence of anemia and consumption of iron-rich food groups in Mexican children and adolescents: Ensanut MC 2016. Salud Publica Mex. 2018;60(3):291-300. https://doi.org/10.21149/8824

  6. 6.Wang M. Iron Deficiency and other types of anemia in infants and children. Am Fam Physician. 2016;93(4):270-8. Available from: https://www. aafp.org/afp/2016/0215/p270.html

  7. Wirth JP, Petry N, Tanumihardjo SA, Rogers LM, McLean E, Greig A, et al. Vitamin a supplementation programs and country-level evidence of vitamin A deficiency. Nutrients. 2017;9(3):1-18. https://doi.org/10.3390/ nu9030190

  8. Lozoff B, Beard J, Connor J, Felt B, Georgieff M, Schallert T. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev. 2006;64(suppl 2):S34-S43. https://doi.org/10.1111/j.1753-4887.2006. tb00243.x

  9. Wirth JP, Woodruff BA, Engle-Stone R, Namaste SM, Temple VJ, Petry N, et al. Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. Am J Clin Nutr. 2017;106(suppl):416S-27S. Available from: https:// www.ncbi.nlm.nih.gov/pmc/articles/PMC5490645/pdf/ajcn143073.pdf

  10. Romero-Martínez M, Shamah-levy T, Vielma-Orozco E, Heredia- Hernández O, Mojica-Cuevas J, Cuevas-Nasu L, et al. Encuesta Nacional de Salud y Nutrición 2018-19: Metodología y perspectivas. Salud Publica Mex. 2019;61(6):917-23. https://doi.org/10.21149/11095

  11. Shamah-Levy T, Villalpando-Hernández S, Rivera-Dommarco J. Manual de procedimientos para proyectos de nutrición (Manual of procedures for nutrition interventions). Cuernavaca, México: Instituto Nacional de Salud Pública, 2006 [cited August, 2020]. Available from: http://www.salud.gob. mx/unidades/cdi/documentos/proy_nutricion.pdf2

  12. Rivera JA, Sotres-Alvarez D, Habicht JP, Shamah T, Villalpando S. Impact of the Mexican program for education, health, and nutrition (Progresa) on rates of growth and anemia in infants and young children: A randomized effectiveness study. J Am Med Assoc. 2004;291(21):2563-70. https://doi. org/10.1001/jama.291.21.2563

  13. Rivera JA, Shamah T, Villalpando S, Monterrubio E. Effectiveness of a large-scale iron-fortified milk distribution program on anemia and iron deficiency in low-income young children in Mexico. Am J Clin Nutr. 2010;91(2):431-9. https://doi.org/10.3945/ajcn.2009.28104

  14. Lohman T, Roche A, Martorell R. Anthropometric standarization reference manual. Champlaign, IL: Human Kinetics, 1988.

  15. Habicht JP. Standardization of anthropometric methods in the field. PAHO Bull. 1974;76(5):375-84.

  16. Members of the WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Ginebra: WHO, 2007.

  17. Cohen JH, Haas JD. Hemoglobin correction factors for estimating the prevalence of iron deficiency anemia in pregnant women residing at high altitudes in Bolivia. Rev Panam Salud Publica/Pan Am J Public Heal. 1999;6(6):392-9. https://doi.org/10.1590/S1020-49891999001100004

  18. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System. Geneva: WHO, 2011 [cited August, 2020]. Available from: http://www.who.int/vmnis/indicators/haemoglobin.pdf

  19. Thurnham DI, McCabe LD, Haldar S, Wieringa FT, Northrop-Clewes CA, McCabe GP. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: A meta-analysis. Am J Clin Nutr. 2010;92(3):546-55. https://doi.org/10.3945/ ajcn.2010.29284

  20. Delforge M, Selleslag D, Triffet A, Mineur P, Bries G, Graux C, et al. Iron status and treatment modalities in transfusion-dependent patients with myelodysplastic syndromes. Ann Hematol. 2011;90(6):655-66. https://doi. org/10.1007/s00277-011-1164-9

  21. World Health Organization. Serum retinol concentrations for determining the prevalence of vitamin A deficiency in populations. Geneva: WHO, 2011 [cited August, 2020]. Available from: http://www.who.int/ vmnis/indicators/retinol.pdf

  22. Ankar A, Kumar A. Vitamin B12 Deficiency (Cobalamin). Treasure Island (FL): StatPearls Publishing; 2020 [cited August, 2020]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441923/

  23. Flores ME, Rivera-Pasquel M, Valdez-Sánchez A, De la Cruz-Góngora V, Contreras-Manzano A, Shamah-Levy T, Villalpando S. Vitamin D status in Mexican children 1 to 11 years of age: an update from the National Survey (Ensanut) Mexico, 2018-19. Salud Publica Mex. 2021. https://doi. org/10.21149/12156

  24. De la Cruz-Góngora V, Shamah-Levy T, Villalpando S, Méndez-Gómez Humarán I, Rebollar-Campos R, Rivera-Dommarco J. A decreasing trend in zinc deficiency in Mexican children aged 1-4: analysis of three national health and nutrition surveys in 1999, 2006 and 2018-19. Salud Publica Mex. 2021. https://doi.org/10.21149/12157

  25. Hans KB, Tinz J.Micronutrients in the life cycle: Requirements and sufficient supply. NFS Journal. 2018;11:1-11. https://doi.org/10.1016/j. nfs.2018.03.001 26.Gombart AF, Pierre A, Maggini S. A review of micronutrients and the immune system-working in harmony to reduce the risk of infection. Nutrients. 2020;12(1):1-41. https://doi.org/10.3390/nu12010236

  26. Chaparro CM, Suchdev PS. Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Ann N Y Acad Sci.2019;1450(1):15-31. https://doi.org/10.1111/nyas.14092

  27. Semba RD, Bloem MW. The anemia of vitamin A deficiency: epidemiology and pathogenesis. Eur J Clin Nutr. 2002;56(4):271-81. https://doi. org/10.1038/sj/ejcn/1601320

  28. Aigner E, Feldman A, Datz C. Obesity as an Emerging risk factor for iron deficiency. Nutrients. 2014;6(9):3587-600. https://doi.org/10.3390/ nu6093587

  29. Cepeda-Lopez AC, Aeberli I, Zimmermann MB. Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res. 2010;80(4-5):263-70. https://doi. org/10.1024/0300-9831/a000033

  30. Suri DJ, Tanumihardjo JP, Gannon BM, Pinkaew S, Kaliwile C, Chileshe J, et al. Serum retinol concentrations demonstrate high specificity after correcting for inflammation but questionable sensitivity compared with liver stores calculated from isotope dilution in determining Vitamin A deficiency in Thai and Zambian children. Am J Clin Nutr. 2015;102(5):1259-65. https://doi.org/10.3945/ajcn.115.113050

  31. Mills JP, Furr HC, Tanumihardjo SA. Retinol to Retinol-Binding Protein (RBP) is low in obese adults due to elevated apo-RBP. Exp Biol Med. 2008; 233(10):1255-61. https://doi.org/10.3181/0803-RM-94

  32. Rahman MM, Wahed MA, Fuchs GJ, Baqui AH, Alvarez JO. Synergistic effect of zinc and vitamin A on the biochemical indexes of vitamin A nutrition in children. Am J Clin Nutr. 2002;75(1):92-8. https://doi.org/10.1093/ ajcn/75.1.92

  33. World Health Organization. Guideline: Vitamin A supplementation in infants and children 6-59 months of age. Geneva: WHO, 2011.

  34. World Health Organization. Global strategy for infant and young child feeding. Fifthy-fourth world Healh Assembly, Geneva: WHO, 2002.




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