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2020, Number 4

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Dermatología Cosmética, Médica y Quirúrgica 2020; 18 (4)

Primary Cutaneous Histoplasmosis. Case Report

Castro CLP, Gómez CCF, Uhia CA, Celis LG

Language: Spanish
References: 33
Page: 281-286
PDF size: 340.81 Kb.


ABSTRACT

Histoplasmosis is considered the most frequent respiratory system mycosis, caused by Histoplasma capsulatum var. capsulatum. In South America it is observed in Colombia. In endemic areas, H. capsulatum is a primary pathogen but becomes an opportunistic pathogen in cases of underlying immunosuppression. People with occupations such as miners, engineers and similar professions have a higher risk of contracting the infection. Primary cutaneous histoplasmosis is a rare condition; majority of cases occur due to traumatic implantation obtaining a unique non-specific lesion.
We present a 43-year-old female, with a six-month history of skin lesion on the left nostril, associated with nasal congestion and rhinorrhea. Previously treated with antihistamines without improvement. It was evaluated by dermatology with a positive skin biopsy report for Histoplasma. ELISA test was requested for HIV as well as hepatitis c and b antibody, with negative results. Treatment with amphotericin b is initiated and switched after eight days to itraconazole with satisfactory evolution. Ambulatory treatment with oral antifungal for 12 weeks.


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