2019, Number 3
Effectiveness of oleozon in the treatment of recurrent aphthous stomatitis
Language: Spanish
References: 7
Page: 297-304
PDF size: 357.80 Kb.
ABSTRACT
Introduction: recurrent aphthous stomatitis is one of the most frequent and painful alterations of the oral complex.Objective: to evaluate the effectiveness of oleozon in the treatment of recurrent aphthous stomatitis.
Method: a randomized controlled phase IV clinical trial was carried out on 120 patients aged 15 to 35 years, with a clinical diagnosis of recurrent aphthous stomatitis who attended the emergency department of the Mayarí Stomatological Clinic, Holguín province, between April 2017 and February 2018. Oleozon was applied to the study group, and the conventional drug treatment was applied to the control group. The bioethical principles defined for this type of study were fulfilled.
Results: stomatitis predominated in the study group at the ages of 25 to 35 years (63,33 %) and in the female sex (75,00 %). It was observed that the majority of patients treated with ozonized oil (93,33 %) healed on the seventh day. However, in the control group only 56,67 % healed.
Conclusions: oleozon is effective in the aphthae healing, with a shorter therapeutic response time than conventional treatment.
REFERENCES
Troya-Borges E, Martínez-Abreu J, Padilla-Suárez E, Iglesias-López N, Ramos-Ortega A. La estomatitis aftosa recurrente y las situaciones de estrés como factor de riesgo. Rev Méd Electrón [Internet]. Dic 2014 [citado 6 Feb 2018];36(6):799-812. Disponible en: http://scielo.sld.cu/pdf/rme/v36n6/rme010614.pdf
Martínez-Abreu J, Guerra-Fontén N, Blanco-García A, Naranjo-Rodríguez S, Llanes-Llanes E, Menéndez-Cepero S. Efficacy of OLEOZON® compared to Alvogil in the treatment of alveolitis. Journal of Ozone Therapy [Internet]. 2015. [citado 23 Mar 2018];1(1):[aprox. 8p.]. Disponible en: https://ojs.uv.es/index.php/JO3T/article/download/12162/pdf
Casado-Tamayo D, Quezada-Oliva LM, Casado-Méndez PR, Santos-Fonseca RS, Méndez-Jiménez O, Pérez-Villavicencio AM. Efectividad del tratamiento con oleozón versus crema de aloe en la estomatitis subprotésica. AMC [Internet]. Abr 2017 [citado 23 Mar 2018];21(2):202-12. Disponible en: http://scielo.sld.cu/pdf/amc/v21n2/amc050217.pdf