2019, Number 4
Congenital heart disease in the main aneuploidy syndromes
Language: Spanish
References: 12
Page: 353-355
PDF size: 168.95 Kb.
Text Extraction
To the Editor:In a world where there is a rise in the socio-economic development and progress in the control of infectious diseases and malnutrition, congenital malformations are presented as a health problem. These malformations, in general, are defined as inadequate tissue formation due to genetic defects themselves, where genetic abnormality affects genes involved in the development1. According to Acosta and Mullings, the frequency of congenital malformations in humans is estimated in one out of 16 newborns and they are responsible for 15% of deaths that take place in the first year of life, and therefore, they represent the leading cause of mortality in infants.
Meanwhile, congenital heart diseases are disorders present at the time of birth due to alterations in the form and function of the heart, the circulatory system and great vessels, that appear during the cardiac embryogenesis. Tassinari et al 2 suggest that they are among the most frequent congenital anoma-lies with the highest mortality in the world, with a prevalence that can vary between 0.04-0.19, and reach up to 80 cases per 10.000 live births.
REFERENCES
Mocarbel Y, Arébalo de Cross G, Lebrethon MC, Thiry A, Beckers A, Valdes-Socin H. Asociación de craneofaringioma y síndrome de Klinefelter en la transición puberal: un desafío diagnóstico. Arch Argent Pediatr [Internet]. 2017 [cited 22 Ago 2019];115(2):e104-7. Available at: https://www.sap.org.ar/docs/publicaciones/archivosarg/2017/v115n2a22.pdf
Aguilar MJ, Zabala ML, López Morales H, Urquijo S, López M. La teoría de la mente como proceso mediador del funcionamiento social. Evaluación en el Síndrome de Turner. Rev Argent Cien Comport [Internet]. 2016 [cited 22 Ago 2019]; 8(3):40-7. Available at: https://revistas.unc.edu.ar/index.php/racc/article/view/14329/Aguilar_1216