2020, Number 1
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Med Cutan Iber Lat Am 2020; 48 (1)
Merkel cell carcinoma. A retrospective observational study (1998-2018) in a University Hospital
González-Romero N, Lobato-Izagirre A, Blanch-Rius L, Cancho-Galán G, Izu-Belloso R
Language: Spanish
References: 13
Page: 63-68
PDF size: 201.20 Kb.
ABSTRACT
Introduction: Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm with a poor prognosis. There is no consensus to address its management.
Material and methods: We performed a search of patients with histological diagnosis of MCC from 1998 to 2018 (n = 20), in the database of our hospital and we collected next data: sex, age, history of immunosuppression, skin cancer no melanoma and malignant melanoma, initial diagnosis suspicion, tumor size, location, staging, treatments received, evolution and survival.
Results: The majority of lesions (40%) were located in the face and neck and 50% had 2 to 5 cm. 85% of the patients received surgical treatment, 75% had RT. 50% of patients had recurrence, all before the first 24 months. In our sample, we observed that survival is greater in patients with lesions smaller than 2 cm, located in extremities, positive for polyomavirus, in those who have received adjuvant RT and in those without affected surgical.
Conclusions: We have observed five factors associated with grater survival, which, although not statistically significant, are clinically relevant and concur with those of other series.
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