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Colegio de Medicina Interna de México.

2020, Number 2

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Med Int Mex 2020; 36 (2)

HIV and tuberculosis concomitant to Kaposi’s sarcoma and other opportunistic infections. Care at a reference hospital in Tabasco, Mexico

Márquez-Quiroz O, Flores-Barrientos O, Gónzales-Romo MA

Language: Spanish
References: 51
Page: 255-264
PDF size: 261.76 Kb.


ABSTRACT

Background: HIV infection increases the risk of active tuberculosis; both entities are a frequent cause of mortality worldwide. HIV manipulates the production of cytokines which favors bacterial dissemination, in turn, the replication of HIV is induced by macrophages infected by M. tuberculosis. The binomial HIV and tuberculosis is associated with high morbidity and mortality, so in patients with HIV it is important the early diagnosis and treatment of tuberculosis, both in its active and latent form.
Clinical cases: This paper reports two cases of patients with AIDS in which there was coexistence of Kaposi’s sarcoma and disseminated tuberculosis, as well as other opportunistic infections.
Conclusion: After the introduction of antiretroviral drugs, the mortality and morbidity of patients with human immunodeficiency virus infection have decreased; however, Kaposi’s sarcoma remains a frequent malignancy in these patients and is still associated with significant mortality.


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