Recinos-Money E, Zepeda-Castilla E, Pérez-Castro J, Escobar-Alfaro G, Aragón-Castro M

Language: Spanish
References: 14
Page: 231-234
PDF size: 207.20 Kb.

ABSTRACT

The primary renal lymphoma is a rare disease whose etiology and pathogenesis are not yet well defined, so much so, its existence is in doubt. This explains the multiple ways to treat it. This paper reports the case of a male patient of 56 years old who consulted for incidental finding of creatinine 2 mg/dL. Abdominal US showed a left renal tumor. Thoracic and abdomino-pelvic tomography corroborated a left renal tumor. Left radical nephrectomy was performed. The pathology report was a diffuse non-Hodgkin large cell type B lymphoma. Bone marrow aspiration was negative. Patient received six cycles of chemotherapy with cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab scheme, in addition, maintenance for 2 years with rituximab bimonthly. The patient is disease-free after 96 months of follow-up and has normal creatinine. Primary renal lymphoma affects 60 years old men with highly variable symptoms. The diagnosis is very difficult by clinic or images and is usually performed by the histology of nephrectomy. Diffuse non-Hodgkin large cell type B lymphoma is the most common subtype. Currently, treatment consists of systemic chemotherapy and rituximab and survival has improved greatly with this scheme.

REFERENCES

1. Kandel LB, McCullough DL, Harrison LH, Woodruff RD, Ahl ET, Munitz HA. Primary renal lymphoma. Does it exist? Cancer 1987;60:386-391.

2. Hagihara M, Hua J, Iwaki Y, Inoue M, Sato T. Primary renal lymphoma: A case report and literature review. Intern Med 2015;54:2655-59.

3. Dobkin SF, Brem AS, Caldamone AA. Primary renal lymphoma. J Urol 1991;146:1588.

4. Lu L, Shi HZ, Xiao ZJ, Wang D, Li CL. Primary renal lymphoma: a clinical analysis of 5 cases. Zhonghua Yi Xue Za Zhi 2018;98(18):1443-1445.

5. Malbrain ML, Lambrecht GL, Daelemans R, Lins RL, Hermans P, Zachée P. Acute renal failure due to bilateral lymphomatous infiltrates. Primary extranodal non-Hodgkin’s lymphoma of the kidneys: Does it really exist? Clin Nephrol 1994;42(3):163-169.

6. Agochukwu NQ, Kilchevsky A, Hesse D. Primary renal large cell B-cell lymphoma imitating invasive renal cell carcinoma with inferior vena cava tumor thrombus. Urol Case Rep 2018;18:84-86.

7. Vazquez-Alonso F, Puche-Sanz I, Sanchez-Ramos C, Flores- Martin J, Vicente-Prados J, Cozar-Olmo JM. Primary renal lymphoma: Long-term results of two patients treated with a chemotherapy+rituximab protocol. Case Rep Oncol Med 2012;2012:726424.

8. Pinggera GM, Peschel R, Buttazzoni A, Mitterberger M, Friedrich A, Pallwein L. A possible case of primary renal lymphoma: A case report. Cases J 2009;2:6233-35.

9. Schniederjan SD, Osunkoya AO. Lymphoid neoplasm of the urinary tract and male genital organs: A clinicopathological study of 40 cases. Mod Pathol 2009;22(8):1057-65.

10. Gupta A, Bhatt A, Khaira A, Gupta A, Ran DS. Primary renal lymphoma: A differential diagnosis of renal mass in a young male. Saudi J Kidney Dis Transpl 2010;21(3):544-545.

11. Hart S, Chandy E, Shafer D, Mehta V, Turk TM. A case of primary renal lymphoma. Urology 2012;80(4):763-765.

12. Pahwa M, Gupta N, Tyagi V, Chadha S. Primary renal lymphoma: Is prognosis really that bad? Saudi J Kidney Dis Transpl 2013;24(4):816-817.

13. Thawani R, Amar A, Patowary J, Kaul S, Jena A, Das PK. Primary renal cell lymphoma: Case report, diagnosis, and management. Indian J Med Paediatr Oncol 2017;38(4):545- 547.

14. Cyriac S, Rejiv R, Shirley S, Sagar GT. Primary renal lymphoma mimicking renal cell carcinoma. Indian J Urol 2010;26(3):441-443.