Ávila VN, Fritche‑Salazar JF, Parra‑Ordóñez NA, Herrera‑Bello H

Language: Spanish
References: 14
Page: 78-84
PDF size: 206.69 Kb.

ABSTRACT

Degenerative mitral regurgitation (MR) is a progressive condition, the optimal time for surgical correction often goes unnoticed. Left ventricle (LV) mechanics evolution assessed by echocardiography might be an important diagnostic tool. Currently, little is known about ventricular mechanics and left ventricular compensatory mechanisms to maintain adequate cardiac output in the context of degenerative MR. Our objective was to describe the LV mechanics behavior in patients with different degrees of degenerative MR and compare them with a healthy control group. Methods: An observational, cross-sectional, comparative and analytical study was designed. Ventricular mechanics analysis was performed using GE system. The patients were grouped in mild, moderate or severe MR. Results: Ninety-one participants were included, 57 cases and 34 controls. The case group presented a significant decrease in longitudinal, radial and circumferential strain, as well as, diminution of twist and torsion in relation to the control group. According to the severity of the mitral regurgitation, the global longitudinal strain (GLS) showed a significant progressive decrease from -20%, -18% and -14% in mild, moderate and severe MR respectively, (p=0.03). The same scenario was observed in global circumferential and radial strain; rotational mechanics with twist and torsion decreasing from mild to severe MR (p=0.034, p=0.038 respectively). Conclusion: Alterations in LV mechanics are seen in moderate and severe degrees of MR, this could expose a lack of compensatory mechanisms to maintain ventricular function as the pathology progresses.

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