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ISSN 1405-0625 (Print)

2019, Number 2

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Cir Plast 2019; 29 (2)

Effect of the application of fibrin adhesive (Tissucol®) on the microvascular anastomosis in an animal model

Rodríguez-Salazar MB, Fernández-Riera R, Pacheco-López RC, Vargas-Rocha JM, Pacheco-Escobedo MA

Language: Spanish
References: 23
Page: 196-201
PDF size: 268.89 Kb.


ABSTRACT

Several studies document the use of tissue adhesive in microvascular anastomosis to decrease surgery time, number of sutures and bleeding. Despite encouraging results, it is not generally used in the clinical context. In this study we analyze the reliability and safety of the application of fibrin adhesives in microvascular anastomoses in an animal model. We performed term-terminal microvascular anastomosis after the section of the common iliac arteries of both sides in 13 rats: on one side 8 sutures separated in a habitual way (control) and on the other side 4 equidistant separate stitches adding fibrin adhesive (experimental). The average numbers of stitches were 8 on the control side and 3.9 on the experimental side, with 0.31mL (control) and 0.10 mL (experimental) bleeding; the operative time was 39.5 minutes (control) and 24.4 minutes (experimental); the permeability (absence of thrombosis) was 100% (control) and 92.3% (experimental). We conclude that the application of fibrin adhesive in microvascular anastomosis in rats is effective and reduces surgical time.


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