2019, Number 1
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Cir Plast 2019; 29 (1)
Case of death by liposculpture: Medical opinion
Cuenca-Pardo J
Language: Spanish
References: 56
Page: 120-146
PDF size: 384.19 Kb.
ABSTRACT
The alterations that occur prior to the sudden death of patients operated on liposuction are hypotension, bradycardia, oxygen desaturation and asystole. The causes are fatty embolism, anesthetic poisoning, and vagal reflex due to high epidural block and toxic heart disease due to cocaine use. In the last four years we have identified six cases in similar conditions; we present the expert opinion of one of them. A case of a 43-year-old woman addicted to cocaine with prior liposuction; body weight 65 kg and height 1.65 m. A liposuction of the abdomen, sides and back was performed, having used saline solution + 1 vial of adrenaline for vasoconstriction, 3,000 mL and 300 mL of fat infiltrate in each buttock was aspirated. A double epidural block with 3 doses of anesthetics was used. The third dose of anesthetics coincided with fatty infiltration. In this moment the patient presented hypotension, bradycardia and oxygen desaturation that in a few minutes evolved to asystole. She did not respond to resuscitation maneuvers. The forensic pathology study reported vacuoles compatible with fat and established fulminant massive fat embolism, the cause of death. There are several mortal nosological entities that can occur during a liposculpture, all have similar clinical manifestations. Severity depends on the way the patient responds and they are difficult to diagnose and treat. With the data obtained and the report of the forensic study, the cause of death cannot be determined categorically. Studies are needed to look for these pathologies to establish the true diagnosis.
REFERENCES
Dolsky RL. State of the art in liposuction. Dermatol Surg 1997; 23: 1192-1193.
Klein J. Anesthetic formulations of tumescent solutions. In: Dermatological clinics (W.P. Coleman III, Ed). Philadelphia, WB Saunders,17:4:751-759, 1999.
Rao RB, Ely SF, Hoffman RS. Deaths related to liposuction. N Engl J Med 1999; 340 (19): 1471-1475.
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Dermatol Surg Oncol 1990; 16: 248-263.
Ostad A, Kageyama N, Moy RL. Tumescent anesthesia with lidocaine dose of 55 mg/kg is safe for liposuction. Dermatol Surg 1996; 22: 921-927.
Burk RW, Guzman-Stein G, Vasconez LO. Lidocaine and epinephrine levels in tumescent technique liposuction. Plast Reconstr Surg 1996; 97: 1379-1384.
Butterwick KJ, Goldman MP, Sriprachya-Anunt S. Lidocaine levels during the first two hours of infiltration of dilute anesthetic solution for tumescent liposuction: rapid versus slow delivery. Dermatol Surg 1999; 25: 681-685.
Kenkel JM, Lipschitz AH, Shepherd G, Armstrong VW, Streit F, Oellerich M et al. Pharmacokinetics and safety of lidocaine and monoethylglycinexylidine in liposuction: a microdialysis study. Plast Reconstr Surg 2004; 114: 516-524.
Rubin JP, Xie Z, Davidson C, Rosow CE, Chang Y, May JW Jr. Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study. Plast Reconstr Surg 2005; 115: 1744-1751.
Nordstrom H, Stange K. Plasma lidocaine levels and risks after liposuction with tumescent anesthesia. Acta Anaesthesiol Scand 2005; 49: 1487-1490.
Ramirez-Guerrero JA. Liposucción. Consideraciones anestésicas y perioperatorias. Rev Mex Anest 2007; 30 (4): 233-241.
Rubin JP, Bierman C, Rosow CE, Arthur GR, Chang Y, Courtiss EH et al. The tumescent technique: the effect of high tissue pressure and dilute epinephrine in absorption of lidocaine. Plast Reconstr Surg 1999; 103: 990-996.
Burk RW. Large doses of lidocaine, epinephrine and fluids in abdominal liposuction. Oper Techn Plast Surg 1996; 3: 35-38.
Hanke CW, Bernstein G, Bullok S. Safety of tumescent liposuction in 15,336 patients. National survey results. Dermatol Surg 1995; 21: 459-462.
Katz BE, Bruck MC, Felsenfeld L, Frew KE. Power liposuction: report on complications. Dermatol Surg 2003; 29: 925-927.
Bernstein G, Hanke CW. Safety of liposuction: a review of 9478 cases. Performed by dermatologists. J Dermatol Surg Oncol 1988; 14: 1112-1114.
Hanke CW, Bullock S, Bernstein G. Current status of tumescent liposuction in the United States: national survey results. Dermatol Surg 1996; 22: 595-598.
Hoefflin SM, Bornstein JB, Gordon M. General anesthesia in an office-based plastic surgical facility: a report on more than 23000 consecutive office-based procedures under general anesthesia with no significant anesthetic complications. Plats Reconstr Surg 2001; 107:243-251.
Scarborough DA, Herron JB, Khan A, Bisaccia E. Experience with more than 5,000 cases in which monitored anesthesia care was used for liposuction surgery. Aesthetic Plast Surg 2003; 27: 474-480.
Johnson PJ. General anesthesia in an office-based plastic surgical facility: a report on more than 23,000 consecutive office-based procedures under general anesthesia with no significant anesthetic complications. Arch Facial Plast Surg 2001; 3: 287.
Ibarra P, Arango J, Bayter J, Castro J, Cortés J, Lascano M et al. Consenso de la Sociedad Colombiana de Anestesiología y Reanimación, SCARE y de la Sociedad Colombiana de Cirugía Plástica, sobre las recomendaciones para el manejo de pacientes electivos de bajo riesgo. Rev Col Anest 2010; 37 (4): 390-403.
Vila H Jr., Soto R, Cantor AB, Mackey D. Comparative outcomes analysis of procedures performed in physician offices and ambulatory surgery centers. Arch Surg 2003; 138: 991-995.
Iverson RE. Patient safety in office-based surgery facilities: I. Procedures in the office-based surgery setting. Plast Reconstr Surg 2002; 110: 1337-1342.
Iverson RE, Lynch DJ. Patient safety in office-based surgery facilities: II. Patient selection. Plast Reconstr Surg 2002; 110: 1785-1790; discussion 1791-2.
Steve H. Fritz E. Harry H. Safety and efficacy in an accredited outpatient plastic surgery facility: a review of 5316 consecutive cases. Plast Reconstr Surg 2003; 112: 636.
Bitar G, Mullis W, Jacobs W, Matthews D, Beasley M, Smith K et al. Safety and efficacy of office-based surgery with monitored anesthesia care/sedation in 4,778 consecutive plastic surgery procedures. Plast Reconstr Surg 2003; 111 (1): 150-156.
Grazer FM, Jong RH. Fatal outcomes from liposuction. Census survey of cosmetic surgeons. Plast Reconstr Surg 2000; 105: 436-446.
Hughes CE. Reduction of lipoplasty risks and mortality: an ASAPS survey. Anesth Plast Surg 2001; 21: 120-127.
ISAPS International Survey on Aesthetic/Cosmetic Procedures Performed in 2013. Available in: http://www.isaps.org/news/isaps-global-statistics.
Gutowski KA. ASPS Fat Graft Task Force. Current applications and safety of autologous fat grafts: a report of the ASPS Fat Graft Task Force. Plast Reconstr Surg 2009; 124 (1): 272-280.
Kaufman MR, Bradley JP, Dickinson B, Heller JB, Wasson K, O’Hara C et al. Autologous fat transfer national consensus survey: trends in techniques for harvest, preparation, and application, and perception of short- and long-term results. Plast Reconstr Surg 2007; 119 (1): 323-331.
Gir Ph, Brown SA, Oni G, Kashefi N, Mojallal Ali, Rohrich RJ. Fat grafting: evidence-based review on autologous fat harvesting, processing, reinjection, and storage. Plast Reconstr Surg 2012; 130 (1): 249-258.
Murillo WL. Buttock augmentation: case studies of fat injection monitored by magnetic resonance imaging. Plast Reconstr Surg 2004; 114 (6): 1606-1614.
Cárdenas-Camarena L, Lacouture AM, Tobar-Losada A. Combined gluteoplasty: liposuction and lipoinjection. Plast Reconstr Surg 1999; 104 (5): 1524-1531.
Cárdenas-Camarena L, Arenas-Quintana R, Robles-Cervantes JA. Buttocks fat grafting: 14 years of evolution and experience. Plast Reconstr Surg 2011; 128 (2):545-555.
Kenkel JM, Brown SA, Love EJ, Waddle JP, Krueger JE, Noble D et al. Hemodynamics, electrolytes and organ histology of larger-volume liposuction in a porcine model. Plast Reconstr Surg 2004; 113: 1391-1399.
Kenkel JM, Lipschitz AH, Luby M et al. Hemodynamic physiology and thermoregulation in liposuction. Plast Reconstr Surg 2004; 114: 503-513.
Fourme T, Vieillard-Baron A, Loubières Y, Julié C, Page B, Jardin F. Early fat embolism after liposuction. Anesthesiology. 1998; 89 (3): 782-784.
Ross R, Johnson G. Fat embolism after liposuction. Chest 1988; 93: 1294-1295.
Taviloglu K, Yanar H. Fat embolism syndrome. Surg Today 2007; 37: 5-8.
Araujo Felsemburgh V. Cavalcante das Neves Barbosa R, Correira Nunes VL, Oliveira Campos JH. Fat embolism in liposuction and intramuscular graft in Rabbits. Acta Cirúrgica Br 2012; 27 (5): 289-293.
Correa S, Torres C, Barreto L, Granados C. Lipuria y macroglobulinemia grasa en liposucción. Rev Col Cir Plast Reconstr 2011; 17 (2): 22-28.
Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, Howland MA, Hoffman RS, eds. Goldfrank’s toxicological emergencies. 5th ed. Norwalk, Conn.: Appleton & Lange 1994, pp. 717-719.
Lillis PJ. Liposuction surgery under local anesthesia: limited blood loss and minimal lidocaine absorption. J Dermatol Surg Oncol 1988; 14: 1145-1148.
Samdal F, Amland PF, Bugge JF. Plasma lidocaine levels during suction assisted lipectomy using large doses of dilute lidocaine with epinephrine. Plast Reconstr Surg 1994; 93: 1217-1223.
Klein JA. The tumescent technique: anesthesia and modified liposuction technique. Dermatol Clin 1990; 8: 425-437.
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Dermatol Surg Oncol 1990; 16: 248-263.
Parkinson A. Biotransformation of xenobiotics. In: Klaassen CD, ed. Casarett and Doull’s toxicology: the basic science of poisons. 5th Ed. New York: McGraw-Hill 1996, pp. 113-86.
Prouty RW, Anderson WH. The forensic science implications of site and temporal influences on postmortem blood-drug concentrations. J Forensic Sci 1990; 35: 243-270.
Peat MA, Deyman ME, Crouch DJ, Margot P, Finkle BS. Concentrations of lidocaine and monoethylglycylxylidide (MEGX) in lidocaine associated deaths. J Forensic Sci 1985; 30: 1048-1057.
McAllister RK, Meyer TA, Bittenbinder TM. Can local anesthetic-related deaths during liposuction be prevented? Plast Reconstr Surg 2008; 122 (6): 232e-233e.
Weinberg GL, Ripper R, Feinstein DL, Hoffman W. Lipid emulsion infusion rescues dogs from bupivacaine induced cardiac toxicity. Reg Anesth Pain Med 2003; 28: 198.
Weinberg GL, VadeBoncouer T, Ramaraju GA, García-Amaro MF, Cwik MJ. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine induced asystole in rats. Anesthesiology 1998; 88: 1071-1075.
Cuenca-Pardo J, Contreras-Bulnes L, Iribarren-Moreno R, Hernández-Valverde C. Muerte súbita en pacientes de lipoaspiración: recomendaciones preventivas. Estudio analítico. Cir Plast 2014; 24 (1): 16-30.
Kinsella SM, Tuckey JP. Perioperative bradycardia and asystole: relationship to vasovagal syncope and the Bezold-Jarisch reflex. Br J Anaesth 2001; 86: 859-868.
Rivera-Flores J, Chavira-Romero M. Manejo anestésico en el paciente consumidor de drogas. Rev Mex Anest 2005; 28: 217-232.