2019, Número 1
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Cir Plast 2019; 29 (1)
Caso de muerte por lipoescultura: dictamen médico
Cuenca-Pardo J
Idioma: Español
Referencias bibliográficas: 56
Paginas: 120-146
Archivo PDF: 372.71 Kb.
RESUMEN
Las alteraciones previas que se presentan antes de la muerte súbita de aquellos pacientes que son operados de liposucción son: hipotensión, bradicardia, desaturación de oxígeno y asistolia. Las causas suelen ocurrir por embolia grasa, intoxicación por anestésicos, reflejo vagal, bloqueo epidural alto y por cardiopatía tóxica por consumo de cocaína. En los últimos cuatro años, hemos identificado seis casos en condiciones similares; en este trabajo, presentamos el dictamen experimentado en uno de ellos. Se trata del caso de una mujer de 43 años adicta a la cocaína y con una liposucción previa, peso corporal de 65 kg y una estatura de 1.65 m. A esta paciente le realizaron una liposucción del abdomen, costados y espalda; para ello, utilizaron solución salina más una ampolleta de adrenalina para vasoconstricción; le aspiraron 3,000 mL e infiltraron 300 mL de grasa en cada glúteo. Para este procedimiento, utilizaron doble bloqueo epidural con aplicación de tres dosis de anestésicos, sin embargo, la tercera dosis de anestésicos coincidió con la infiltración de grasa, lo que al momento hizo que la paciente presentara hipotensión, bradicardia y desaturación de oxígeno, que en pocos minutos evolucionó a la asistolia. No respondió a las maniobras de resucitación. El estudio de patología forense reportó vacuolas compatibles con grasa y determinó una embolia grasa masiva fulminante como causa de muerte. Son varias las entidades nosológicas mortales que se pueden presentar durante una lipoescultura y además todas presentan manifestaciones clínicas similares. Su severidad depende de la forma de responder de cada paciente, y suelen ser difíciles de diagnosticar y tratar. Con los datos obtenidos y el reporte del estudio forense no se puede determinar en forma categórica cuál causa provocó la muerte, por ello, creemos que hacen falta estudios encaminados a buscar estas patologías para establecer un verdadero diagnóstico.
REFERENCIAS (EN ESTE ARTÍCULO)
Dolsky RL. State of the art in liposuction. Dermatol Surg 1997; 23: 1192-1193.
Klein J. Anesthetic formulations of tumescent solutions. In: Dermatological clinics (W.P. Coleman III, Ed). Philadelphia, WB Saunders,17:4:751-759, 1999.
Rao RB, Ely SF, Hoffman RS. Deaths related to liposuction. N Engl J Med 1999; 340 (19): 1471-1475.
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Dermatol Surg Oncol 1990; 16: 248-263.
Ostad A, Kageyama N, Moy RL. Tumescent anesthesia with lidocaine dose of 55 mg/kg is safe for liposuction. Dermatol Surg 1996; 22: 921-927.
Burk RW, Guzman-Stein G, Vasconez LO. Lidocaine and epinephrine levels in tumescent technique liposuction. Plast Reconstr Surg 1996; 97: 1379-1384.
Butterwick KJ, Goldman MP, Sriprachya-Anunt S. Lidocaine levels during the first two hours of infiltration of dilute anesthetic solution for tumescent liposuction: rapid versus slow delivery. Dermatol Surg 1999; 25: 681-685.
Kenkel JM, Lipschitz AH, Shepherd G, Armstrong VW, Streit F, Oellerich M et al. Pharmacokinetics and safety of lidocaine and monoethylglycinexylidine in liposuction: a microdialysis study. Plast Reconstr Surg 2004; 114: 516-524.
Rubin JP, Xie Z, Davidson C, Rosow CE, Chang Y, May JW Jr. Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study. Plast Reconstr Surg 2005; 115: 1744-1751.
Nordstrom H, Stange K. Plasma lidocaine levels and risks after liposuction with tumescent anesthesia. Acta Anaesthesiol Scand 2005; 49: 1487-1490.
Ramirez-Guerrero JA. Liposucción. Consideraciones anestésicas y perioperatorias. Rev Mex Anest 2007; 30 (4): 233-241.
Rubin JP, Bierman C, Rosow CE, Arthur GR, Chang Y, Courtiss EH et al. The tumescent technique: the effect of high tissue pressure and dilute epinephrine in absorption of lidocaine. Plast Reconstr Surg 1999; 103: 990-996.
Burk RW. Large doses of lidocaine, epinephrine and fluids in abdominal liposuction. Oper Techn Plast Surg 1996; 3: 35-38.
Hanke CW, Bernstein G, Bullok S. Safety of tumescent liposuction in 15,336 patients. National survey results. Dermatol Surg 1995; 21: 459-462.
Katz BE, Bruck MC, Felsenfeld L, Frew KE. Power liposuction: report on complications. Dermatol Surg 2003; 29: 925-927.
Bernstein G, Hanke CW. Safety of liposuction: a review of 9478 cases. Performed by dermatologists. J Dermatol Surg Oncol 1988; 14: 1112-1114.
Hanke CW, Bullock S, Bernstein G. Current status of tumescent liposuction in the United States: national survey results. Dermatol Surg 1996; 22: 595-598.
Hoefflin SM, Bornstein JB, Gordon M. General anesthesia in an office-based plastic surgical facility: a report on more than 23000 consecutive office-based procedures under general anesthesia with no significant anesthetic complications. Plats Reconstr Surg 2001; 107:243-251.
Scarborough DA, Herron JB, Khan A, Bisaccia E. Experience with more than 5,000 cases in which monitored anesthesia care was used for liposuction surgery. Aesthetic Plast Surg 2003; 27: 474-480.
Johnson PJ. General anesthesia in an office-based plastic surgical facility: a report on more than 23,000 consecutive office-based procedures under general anesthesia with no significant anesthetic complications. Arch Facial Plast Surg 2001; 3: 287.
Ibarra P, Arango J, Bayter J, Castro J, Cortés J, Lascano M et al. Consenso de la Sociedad Colombiana de Anestesiología y Reanimación, SCARE y de la Sociedad Colombiana de Cirugía Plástica, sobre las recomendaciones para el manejo de pacientes electivos de bajo riesgo. Rev Col Anest 2010; 37 (4): 390-403.
Vila H Jr., Soto R, Cantor AB, Mackey D. Comparative outcomes analysis of procedures performed in physician offices and ambulatory surgery centers. Arch Surg 2003; 138: 991-995.
Iverson RE. Patient safety in office-based surgery facilities: I. Procedures in the office-based surgery setting. Plast Reconstr Surg 2002; 110: 1337-1342.
Iverson RE, Lynch DJ. Patient safety in office-based surgery facilities: II. Patient selection. Plast Reconstr Surg 2002; 110: 1785-1790; discussion 1791-2.
Steve H. Fritz E. Harry H. Safety and efficacy in an accredited outpatient plastic surgery facility: a review of 5316 consecutive cases. Plast Reconstr Surg 2003; 112: 636.
Bitar G, Mullis W, Jacobs W, Matthews D, Beasley M, Smith K et al. Safety and efficacy of office-based surgery with monitored anesthesia care/sedation in 4,778 consecutive plastic surgery procedures. Plast Reconstr Surg 2003; 111 (1): 150-156.
Grazer FM, Jong RH. Fatal outcomes from liposuction. Census survey of cosmetic surgeons. Plast Reconstr Surg 2000; 105: 436-446.
Hughes CE. Reduction of lipoplasty risks and mortality: an ASAPS survey. Anesth Plast Surg 2001; 21: 120-127.
ISAPS International Survey on Aesthetic/Cosmetic Procedures Performed in 2013. Available in: http://www.isaps.org/news/isaps-global-statistics.
Gutowski KA. ASPS Fat Graft Task Force. Current applications and safety of autologous fat grafts: a report of the ASPS Fat Graft Task Force. Plast Reconstr Surg 2009; 124 (1): 272-280.
Kaufman MR, Bradley JP, Dickinson B, Heller JB, Wasson K, O’Hara C et al. Autologous fat transfer national consensus survey: trends in techniques for harvest, preparation, and application, and perception of short- and long-term results. Plast Reconstr Surg 2007; 119 (1): 323-331.
Gir Ph, Brown SA, Oni G, Kashefi N, Mojallal Ali, Rohrich RJ. Fat grafting: evidence-based review on autologous fat harvesting, processing, reinjection, and storage. Plast Reconstr Surg 2012; 130 (1): 249-258.
Murillo WL. Buttock augmentation: case studies of fat injection monitored by magnetic resonance imaging. Plast Reconstr Surg 2004; 114 (6): 1606-1614.
Cárdenas-Camarena L, Lacouture AM, Tobar-Losada A. Combined gluteoplasty: liposuction and lipoinjection. Plast Reconstr Surg 1999; 104 (5): 1524-1531.
Cárdenas-Camarena L, Arenas-Quintana R, Robles-Cervantes JA. Buttocks fat grafting: 14 years of evolution and experience. Plast Reconstr Surg 2011; 128 (2):545-555.
Kenkel JM, Brown SA, Love EJ, Waddle JP, Krueger JE, Noble D et al. Hemodynamics, electrolytes and organ histology of larger-volume liposuction in a porcine model. Plast Reconstr Surg 2004; 113: 1391-1399.
Kenkel JM, Lipschitz AH, Luby M et al. Hemodynamic physiology and thermoregulation in liposuction. Plast Reconstr Surg 2004; 114: 503-513.
Fourme T, Vieillard-Baron A, Loubières Y, Julié C, Page B, Jardin F. Early fat embolism after liposuction. Anesthesiology. 1998; 89 (3): 782-784.
Ross R, Johnson G. Fat embolism after liposuction. Chest 1988; 93: 1294-1295.
Taviloglu K, Yanar H. Fat embolism syndrome. Surg Today 2007; 37: 5-8.
Araujo Felsemburgh V. Cavalcante das Neves Barbosa R, Correira Nunes VL, Oliveira Campos JH. Fat embolism in liposuction and intramuscular graft in Rabbits. Acta Cirúrgica Br 2012; 27 (5): 289-293.
Correa S, Torres C, Barreto L, Granados C. Lipuria y macroglobulinemia grasa en liposucción. Rev Col Cir Plast Reconstr 2011; 17 (2): 22-28.
Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, Howland MA, Hoffman RS, eds. Goldfrank’s toxicological emergencies. 5th ed. Norwalk, Conn.: Appleton & Lange 1994, pp. 717-719.
Lillis PJ. Liposuction surgery under local anesthesia: limited blood loss and minimal lidocaine absorption. J Dermatol Surg Oncol 1988; 14: 1145-1148.
Samdal F, Amland PF, Bugge JF. Plasma lidocaine levels during suction assisted lipectomy using large doses of dilute lidocaine with epinephrine. Plast Reconstr Surg 1994; 93: 1217-1223.
Klein JA. The tumescent technique: anesthesia and modified liposuction technique. Dermatol Clin 1990; 8: 425-437.
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Dermatol Surg Oncol 1990; 16: 248-263.
Parkinson A. Biotransformation of xenobiotics. In: Klaassen CD, ed. Casarett and Doull’s toxicology: the basic science of poisons. 5th Ed. New York: McGraw-Hill 1996, pp. 113-86.
Prouty RW, Anderson WH. The forensic science implications of site and temporal influences on postmortem blood-drug concentrations. J Forensic Sci 1990; 35: 243-270.
Peat MA, Deyman ME, Crouch DJ, Margot P, Finkle BS. Concentrations of lidocaine and monoethylglycylxylidide (MEGX) in lidocaine associated deaths. J Forensic Sci 1985; 30: 1048-1057.
McAllister RK, Meyer TA, Bittenbinder TM. Can local anesthetic-related deaths during liposuction be prevented? Plast Reconstr Surg 2008; 122 (6): 232e-233e.
Weinberg GL, Ripper R, Feinstein DL, Hoffman W. Lipid emulsion infusion rescues dogs from bupivacaine induced cardiac toxicity. Reg Anesth Pain Med 2003; 28: 198.
Weinberg GL, VadeBoncouer T, Ramaraju GA, García-Amaro MF, Cwik MJ. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine induced asystole in rats. Anesthesiology 1998; 88: 1071-1075.
Cuenca-Pardo J, Contreras-Bulnes L, Iribarren-Moreno R, Hernández-Valverde C. Muerte súbita en pacientes de lipoaspiración: recomendaciones preventivas. Estudio analítico. Cir Plast 2014; 24 (1): 16-30.
Kinsella SM, Tuckey JP. Perioperative bradycardia and asystole: relationship to vasovagal syncope and the Bezold-Jarisch reflex. Br J Anaesth 2001; 86: 859-868.
Rivera-Flores J, Chavira-Romero M. Manejo anestésico en el paciente consumidor de drogas. Rev Mex Anest 2005; 28: 217-232.