Hernández PG, Laguna MKD, Reyes GM, Moreno PJR, Matuz MD

Language: Spanish
References: 44
Page: 93-99
PDF size: 460.54 Kb.

ABSTRACT

Lipids are highly hydrophobic molecules and therefore insoluble in the aqueous component of the blood, so they must be transported through lipoproteins. High density lipoproteins (HDL) are the smallest, with the highest apoprotein content and lowest TAG content; they are synthesized in liver and small bowel, remove cholesterol from peripheral tissues and return it to the liver, which is why they have traditionally been given the protective role in atherogenesis. There are different subtypes of HDL, one of which, the subtype HDL pre-β1, unlike the protective role of the rest, has been related to the development of atherosclerosis. The aim of this article is to review the interaction of HDL with remodeling proteins affecting its composition and/or function, as well as the association of an HDL subtype with cardiovascular risk.

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