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ISSN 1405-1699 (Print)
Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2019, Number 2

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Alerg Asma Inmunol Pediatr 2019; 28 (2)

Screening opportunity for severe combined immunodeficiency in Mexico

Rodríguez CS, Espinosa PSE

Language: Spanish
References: 44
Page: 51-57
PDF size: 183.86 Kb.


ABSTRACT

Severe combined immunodeficiency comprises a variety of genetic defects that, with different patterns of cellular deficiency, are frequently lethal during the first years of life. However, it is now; throughout different techniques, a very treatable disease with excellent prognosis if recognized during the first three months of life. Advances in technology, the discovery and reliability of T-cell excision circles (TREC’s), and big-scale implementation have rended screening affordable mainly in the United States. In Mexico, diagnosis and treatment are also a reality; therefore aiming to screen for this disorders is an important step to prevent big-scale complications and derived costs.


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