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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2019, Número 2

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Alerg Asma Inmunol Pediatr 2019; 28 (2)


Tamizaje de inmunodeficiencia combinada grave y su oportunidad para implementarse en México

Rodríguez CS, Espinosa PSE

Idioma: Español
Referencias bibliográficas: 44
Paginas: 51-57
Archivo PDF: 183.86 Kb.


RESUMEN

La inmunodeficiencia combinada grave comprende una variedad de defectos génicos que, con distintos patrones de deficiencia inmunitaria celular, pueden ser letales durante los primeros años de vida. Sin embargo, existen distintos métodos para detectarla y tratarla. Si esto ocurre durante los primeros meses de vida, el pronóstico es excelente. Los avances en la tecnología y la viabilidad de los círculos de excisión de células T (TRECs) y su implementación a gran escala, principalmente en Estados Unidos, han demostrado que el tamizaje es eficaz y costo-efectivo. En México, el diagnóstico y tratamiento de estos defectos son ya una realidad, por lo que incluirlos en el tamiz neonatal es una oportunidad para prevenir a gran escala las complicaciones y costos derivados de no diagnosticar y tratar estos padecimientos a tiempo.


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