Physical exploration:  fundamental aspect in the early  diagnosis of primary immunodeficiencies

Rosa Arcelia Cano De La Vega; María Edith González Serrano; Mauricio de la Concha Tiznado; Edna Venegas Montoya; Nancy Esmeralda Jiménez Polvo

2019, Number 2

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Alerg Asma Inmunol Pediatr 2019; 28 (2)

Physical exploration: fundamental aspect in the early diagnosis of primary immunodeficiencies

Cano VRA, González SME, De la Concha TM, Venegas ME, Jiménez PNE

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Language: Spanish
References: 24
Page: 58-69
PDF size: 510.49 Kb.

ABSTRACT

Primary immunodeficiencies are a heterogeneous group of diseases, caused by a defect in the function or development of the immune system, hereditary, usually have a very early presentation, are characterized by repeated infections, as well as autoimmunity, allergy, inflammation or cancer. The definitive treatment in the majority is the transplantation of hematopoietic progenitor cells, to have a greater probability of success, it is indispensable the early diagnosis and prophylactic treatment that assures a higher quality of life. We consider it of vital importance that any first contact physician has the knowledge to be able to identify patients early and refer them in a timely manner. For that reason, we elaborated a guide of signs and findings in the physical examination that the first contact doctor will alert about a probable PID. Conclusion: IDPs are under diagnosed and an early diagnosis is key in the treatment, a very important role is played by first contact physicians, paying special attention to how these patients look and what red flags we can find from the beginning of its manifestations, so that, with a good clinical history and complete clinical exploration can be directed directly to the specialist.

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