2019, Number 12
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Ginecol Obstet Mex 2019; 87 (12)
Istmocele: a systematic review of literature
Alkon-Meadows T, Luna-Rojas M, Hernández-Nieto C, Sandler B
Language: Spanish
References: 35
Page: 820-831
PDF size: 519.66 Kb.
ABSTRACT
Objective: Review the literature on the prevalence, risk factors, symptoms, diagnoses
and treatment of patients with isthmocele.
Method: An electronic search was performed using the following databases: PubMed,
EMBASE and Google Scholar. The following terms, words and their combinations
were used: "Cesarean section defect, uterine niche, isthmocele, uterine sacculation,
uterine diverticulum, uterine pouch, isthmocele diagnosis, segmentocele y isthmocele
treatment”. The primary outcome was the symptoms associated with a cesarean scar
defect. The secondary outcomes were prevalence, risk factors, diagnosis and treatment
of istomocele.
Results: 549 articles were collected, of which 288 were eliminated due to duplication
and 228 did not meet the inclusion criteria; In the end, only 33 articles were analyzed.
A prevalence of 15 to 84% was found in women with a previous caesarean section.
The prevalence of this alteration is correlated with the number of cesarean sections;
the greater the number of caesarean sections, the greater the risk of developing an
isthmocele. Its presence can be symptomatic or asymptomatic. The most common
symptom is abnormal uterine bleeding, occurring in a 28.9% to 82% of the patients.
Up to 88% of cases are diagnosed by a transvaginal ultrasound. A surgical hysteroscopy
was associated with a 56.9% to a 100% improvement of symptoms.
Conclusions: Isthmocele is commonly identified incidentally through a transvaginal
ultrasound and is usually asymptomatic. It can cause abnormal uterine bleeding and
secondary infertility. Its prevalence depends on the diagnostic method used. A surgical
hysteroscopy is the most effective treatment method.
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