2019, Number 3
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Rev Latin Infect Pediatr 2019; 32 (3)
Seroprevalence study of the disease of trypanosomiasis
Field‑Cortázares J, Tinoco‑Gracia L, López‑Valencia G, Tamayo‑Sosa AR, Barreras‑Serrano A, Hori S, Medina‑Basulto GE, González‑Medina Y, Coria‑Lorenzo JJ
Language: Spanish
References: 19
Page: 103-108
PDF size: 142.28 Kb.
ABSTRACT
Introduction: Trypanosomiasis, also known as Chagas disease, is a parasitic disease transmitted by vectors such as the bug and the causative agent is Trypanosoma cruzi. The bug bites the skin of the patient and at the same time, it defecates causing itching and scratching inoculates the parasites. The symptoms are mainly cardiac and digestive, can present hepatomegaly, splenomegaly, pericarditis, myocarditis, heart failure, dilation of esophagus and colon.
Objectives: There are no studies of the presence of trypanosomiasis in the city of Ensenada, BC, for this reason, the objective of this work is to demonstrate the existence of this disease by estimating the seroprevalence by the ELISA serological method in patients who attended 3 clinical analysis laboratories.
Material and methods: This prospective and descriptive study was carried out in the time from April 1, 2015, to March 31, 2016. 139 samples were taken from people who were 1-75 years of age of both sexes from Ensenada, Baja California. The blood sera were analyzed with the Kit Chagas (Trypanosoma cruzi) IgG ELISA
® Immuno-Biological Laboratories, Inc. EUA, which detects IgG antibodies against Trypanosoma cruzi, the dilution of the sera was 1: 100.
Results: The trypanosomiasis seroprevalence was 4.3% (CI
95%, 1.9-9.1%). Of which two were women, representing a total of 1.4% (CI
95%, 0.4-5.0); and four were men, representing a total of 2.8% (CI
95%, 1.1-7.1), in addition, 2 (1.4%) patients under 18 years were seropositive (CI
95%, 0.4-5.0) and 4 (2.8%) older than 18 years (CI
95%, 1.1-7.1).
Conclusions: Through this study, it was confirmed that trypanosomiasis exists in Ensenada, Baja California, so it should be taken into account as a possible differential diagnosis in the health sector.
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