2019, Number S1
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Acta Med 2019; 17 (S1)
Embryo transfer
Roque SAM, Sánchez AA
Language: Spanish
References: 28
Page: 42-47
PDF size: 169.31 Kb.
ABSTRACT
Embryo transfer is the last step of
in vitro fertilization (IVF), which is considered by some authors to be one of the most critical steps, since the variations that may exist between the operator’s experience influence the implantation rate of these embryos. This final step has multiple aspects of evaluation from the logistical details prior to the transfer, which in many cases is full of myths, the technique and the experience of the specialist. As well as, the selection of the embryo to transfer according to its quality and day of development and the quantity of these. The technique for embryo transfer is helped by technology, with the use of ultrasound guidance, which has shown in various metanalyses to increase the pregnancy rate and decrease the rate of ectopic pregnancies. There are very few advances in technology to improve this practice, the innovations in catheters have been few, and the vast majority of reproduction clinics do not have a learning program for this technique. Many factors, some before and others during and after the embryo transfer procedure, can affect the outcome. This emphasizes the importance of having all the variables of this practice in the best possible control, to improve the success rates of our patients.
REFERENCES
Kably-Ambe A, Salazar-López Ortiz C, Serviere-Zaragoza C, Velázquez-Cornejo G, Pérez- Peña E, Santos-Haliscack R et al. Consenso nacional mexicano de reproducción asistida. Ginecol Obstet Mex. 2012; 80 (9): 581-624.
Practice Committee of the American Society for Reproductive Medicine. Performing the embryo transfer: a guideline. Fertil Steril. 2017; 107 (4): 882-896.
Saravelos SH, Li T-C. Embry transfer techniques. Best Pract Res Clin Obstet Gynaecol. 2019; S1521-6934 (18): 30266-30269.
Kably-Ambe A, Carballo-Mondragón E, Roque- Sánchez, Leonor Durán-Monterrosas AM, Campos- Cañas J. Transferencia no selectiva de embrión único: posibilidades de embarazo relacionadas con la experiencia del operador. Ginecol Obstet Mex. 2014; 82 (5): 289-295.
Mansour R, Aboulghar M, Serour G. Dummy embryo transfer: a technique that minimizes the problems of embryo transfer and improves the pregnancy rate in human in vitro fertilization. Fertil Steril. 1990; 54 (4): 678-681.
Groutz A, Lessing JB, Wolf Y, Yovel I, Azem F, Amit A. Cervical dilatation during ovum pick-up in patients with cervical stenosis: effect on pregnancy outcome in an in vitro fertilization-embryo transfer program. Fertil Steril. 1997; 67 (5): 909-911.
Coetsier T, Dhont M. Avoiding multiple pregnancies in-vitro fertilization: who’s afraid of single embryo transfer? Hum Reprod. 1998; 13 (10): 2663-2664.
ASRM Practice Committee. Guidelines on number of ebryos transferred: ASRM Practice Committee Report. Birmingham: American Society for Reproductive Medicine, 1998.
Van Montfoort AP, Fiddelers AA, Janssen JM, Derhaag JG, Dirksen CD, Dunselman GA et al. In unselected patients, elective single embryo transfer prevents all multiples, but results in significantly lower pregnancy rates compared with double embryo transfer: a randomized controlled trial. Hum Reprod. 2006; 21 (2): 338-343.
JOINT SOGC-CFAS. Guidelines for the number of embryos to transfer following in vitro fertilization. Int J Gynaecol Obstet. 2008; 102 (2): 203-216.
Thurin A, Hausken J, Hillensjö T, Jablonowska B, Pinborg A, Strandell A et al. Elective single-embryo transfer versus double-embryo transfer in vitro fertilization. N Engl J Med. 2004; 351 (23): 2392-2402.
Kung F, Chang S, Yang C, Lin Y, Lan K, Huang L et al. Transfer of non-selected transferable day 3 embryos in low embryo producers. Fertil Steril. 2003; 80 (6): 1364-1370.
Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Vercruyssen M, Barudy-Vasquez J et al. Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an IVF/ICSI programme. Hum Reprod. 2002; 17 (10): 2626-2631.
Koryntová D, Moosová M, Rezábek K, Pavelková I, Mára M. Single embryo transfer does not compromise the pregnancy rate in patients with good IVF/ICSI prognosis. Ceska Gynekol. 2005; 70 (6): 435-439.
Brook N, Khalaf Y, Coomarasamy A, Edgeworth J, Braude P. A randomized controlled trial of prophylactic antibiotics (co-amoxiclav) prior to embryo transfer. Hum Reprod. 2006; 21 (11): 2911-2915.
Diedrich K, van der Ven H, al-Hasani S, Krebs D. Establishment of pregnancy related to embryo transfer techniques after in vitro fertilization. Hum Reprod. 1989; 4 (Suppl. 8): 111-114.
Awonuga A, Nabi A, Govindbhai J, Birch H, Stewart B. Contamination of embryo transfer catheter and treatment outcome in vitro fertilization. J Assist Reprod Genet. 1998; 15 (4): 198-201.
Mansour RT, Aboulghar MA. Optimizing the embryo transfer technique. Hum Reprod. 2002; 17 (5): 1149-1153.
Abou-Setta AM, Mansour RT, Al-Inany HG, Aboulghar MM, Aboulghar MA, Serour GI. Among women undergoing embryo transfer, is the probability of pregnancy and live birth improved with ultrasound guidance over clinical touch alone? A systemic review and meta-analysis of prospective randomized trials. Fertil Steril. 2007; 88 (2): 333-341.
Coroleu B, Barri PN, Carreras O, Martínez F, Parriego M, Hereter L et al. The influence of the depth of embryo replacement into the uterine cavity on implantation rates after IVF: a controlled, ultrasound-guided study. Hum Reprod. 2002; 17 (2): 341-346.
Al-Shawaf T, Dave R, Harper J, Linehan D, Riley P, Craft I. Transfer of embryos into the uterus: how much do technical factors affect pregnancy rates? J Assist Reprod Genet. 1993; 10 (1): 31-36.
Amarin ZO, Obeidat BR. Bed rest vs free mobilisation following embryo transfer: a prospective randomised study. BJOG. 2004; 111 (11): 1273-1276.
Abou-Setta AM, Al-Inany HG, Mansour RT, Serour GI, Aboulghar MA. Soft vs firm embryo transfer catheters for assisted repro- duction: a systematic review and meta-analysis. Hum Reprod. 2005; 20 (11): 3114-3121.
Beckers NG, Macklon NS, Eijkemans MJ, Ludwig M, Felberbaum RE, Diedrich K et al. Nonsupplemented luteal phase characteristics after the ad- ministration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in vitro fertilization patients after ovarian stimulation with recombinant follicle-stimulating hormone and GnRH antagonist cotreatment. J Clin Endocrinol Metab. 2003; 88 (9): 4186-4192.
Gelbaya TA, Kyrgiou M, Tsoumpou I, Nardo LG. The use of estradiol for luteal phase support in vitro fertilization/intra- cytoplasmic sperm injection cycles: a systematic review and meta-analysis. Fertil Steril. 2008; 90 (6): 2116-2125.
Pritts EA, Atwood AK. Luteal phase support in infertility treatment: a meta-analysis of the randomized trials. Hum Reprod. 2002; 17 (9): 2287-2299.
Boomsma CM, Macklon NS. Does glucocorticoid therapy in the peri-implantation period have an impact on IVF outcomes? Curr Opin Obstet Gynecol. 2008; 20 (3): 249-256.
Stern C, Chamley L, Norris H, Hale L, Baker HW. A randomized, double-blind, placebo-controlled trial of heparin and aspirin for women with in vitro fertilization implantation failure and antiphospholipid or antinuclear antibodies. Fertil Steril. 2003; 80 (2): 376-383.