2018, Number 3
<< Back Next >>
Rev Cubana Invest Bioméd 2018; 37 (3)
Correlation between SO2/FiO2 and PaO2/FiO2 in patients with respiratory insufficiency in mechanical ventilation
Ameghino BJ, Morales CJ, Apolaya-Segura M
Language: Spanish
References: 21
Page: 1-9
PDF size: 119.95 Kb.
ABSTRACT
Introduction: Patients with mechanical ventilation respiratory insufficiency require
strict control of parameters that indicate the presence of lung damage; One of the
parameters is to assess the relationship between arterial pressure of oxygen and
inspired fraction of oxygen, however, using other less invasive parameters is the
current trend, such as oxygen saturation and inspired oxygen fraction.
Objective: To determine the correlation between the oxygen saturation index/inspired fraction of oxygen and oxygen blood pressure/inspired fraction of oxygen in patients with respiratory insufficiency in a mechanical ventilator.
Methods: An observational correlation study was performed in patients hospitalized
in the Intensive Care Unit. The Pearson coefficient was measured between the
variables arterial oxygen pressure / inspired fraction of oxygen and oxygen saturation/inspired fraction of oxygen at the beginning of the mechanical ventilator, at 24, 48 and 72 hours after the start of mechanical ventilation.
Results: 180 samples from 45 patients were studied, it was found that the
correlation between oxygen saturation / inspired fraction of oxygen and arterial
pressure of oxygen / inspired fraction of oxygen at the beginning of mechanical
ventilator was moderate with r = 0.64 p <0.001, however, the correlation tends to be
stronger in the measurements of 24, 48 and 72 hours with values of r = 0.67 p
<0.001, r = 0.91 p <0.001 and r = 0.92 p <0.001 respectively. Proposing the
following equation = oxygen arterial pressure / inspired fraction of oxygen = 0.8106
(oxygen saturation/inspired fraction) + 54.419.
Conclusions: The use of the index of oxygen saturation/fraction inspired by the
immediate period of use of MV, the correlation with arterial pressure of oxygen/inspired fraction is moderate, but after 24 hours of MV the correlation is strong. Noninvasive methods for the evaluation of oxygenation can be an alternative for clinical follow-up in patients with acute respiratory failure.
REFERENCES
Sarmiento X, Almirall J, Guardiola JJ, Mesalles E, Labarta L, Mate JL, et al. Study on the clinicopathological correlation in the secondary acute respiratory distress syndrome. Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2011;35(1):22-7.
Pandharipande PP, Shintani AK, Hagerman HE, St Jacques PJ, Rice TW, Sanders NW, et al. Derivation and validation of Spo2/Fio2 ratio to impute for Pao2/Fio2 ratio in the respiratory component of the Sequential Organ Failure Assessment score. Crit Care Med. 2009;37(4):1317-21.
Garcia-Prieto E, Amado-Rodriguez L, Albaiceta GM. Monitorization of respiratory mechanics in the ventilated patient. Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2014;38(1):49-55.
Alvarez Lerma F, Sanchez Garcia M, Lorente L, Gordo F, Anon JM, Alvarez J, et al. Guidelines for the prevention of ventilator-associated pneumonia and their implementation. The Spanish "Zero-VAP" bundle. Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2014;38(4):226-36.
González Vélez CL. Correlación SO2/FiO2 con PaO2/FiO2 en niños en ventilación mecánica a grandes alturas: estudio multicéntrico. Universidad del Rosario; 2012.
Carrasco Chavez I. Relación SO2/FiO2 y grado de correlación con el radio de Pa/FiO2 en la evaluación de las alteraciones de la oxigenación pulmonar en neumonia adquirida en la comunidad. Instituto Politecnico Nacional; 2010.
Rice W Todd M, Arthur P, Wheeler MD. Comparison of the Spo2/Fio2 Ratio and the Pao2/Fio2 Ratio in Patients With Acute Lung Injury or ARDS. Ffor the National Institutes of Health, National Heart, Lung, and Blood Institute ARDS Network. Chest. 2007;132(2):418-24.
Lobete C, Medina A, Rey C, Mayordomo-Colunga J, Concha A, Menendez S, et al. Correlation of oxygen saturation as measured by pulse oximetry/fraction of inspired oxygen ratio with Pao2/fraction of inspired oxygen ratio in a heterogeneous sample of critically ill children. Journal of critical care. 2013;28(4):538
Miranda MC, Lopez-Herce J, Martinez MC, Carrillo A. Relationship between PAO2/FIO2 and SATO2/FIO2 with mortality and duration of admission in critically ill children. Barcelona, Spain: Anales de pediatria. 2012;76(1):16-22.
Malicdem MGP, Banzon AG. Determination of the utility of the spo2/fio2 ratio in the diagnosis of patients admitted at the philippine heart center with acute lung injury or acute respiratory distress syndrome: A cross-sectional study. CHEST Journal. 2010;138:222A-A.
Gómez A LL, Quijano M. Utilidad de la relación Sao2/Fio2 en la evaluación del grado de compromiso pulmonar en pacientes críticos. Revista de la Facultad de Medicina - Universidad Nacional de Colombia. 2002;50(2):2-7.
Murcia H FJ. Estudio de correlación entre la PAO2/FIO2 y la SO2/FIO2 en niños en ventilación mecanica de la fundación cardioinfantil en Bogotá entre Abril y Junio de 2011. Bogotá: Facultad de Medicina, Universidad del Rosario. 2011. p. 1-49.
Rincón J. Correlación de los índices PaO2/FiO2 y SpO2/FiO2 en el postoperatorio de cirugía cardiaca en una Unidad de Terapia Postquirúrgica Cardiovascular. Revista de la Asociación Mexicana de Medicina Crítica y Terapia Intensiva. 2013;27(2):71-6.
Camargo GD. Comparación de la razón saturometría de pulso/fracción inspirada de oxígeno (SA/FIO2) y la razón presión arterial de oxígeno/fracción inspirada de oxígeno (PO2/FIO2) en pacientes con insuficiencia respiratoria aguda. Acta Colombiana de Cuidado Intensivo. 2011;11(2):86-90.
Cardinal-Fernandez P, Nin N, Lorente JA. Acute lung injury and acute respiratory distress syndrome: a genomic perspective. Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2011;35(6):361-72.
Rodríguez Reyes Oscar RCOB, Marberty Giro Judith. Índice de oxigenación arterial en pacientes con sepsis respiratoria ventilados. MEDISAN. 2010;14(2):225-31.
Khemani Robider TN, Venkatachalan Vani, Scimeme Jason, Sneider James, Ross Patrik. Comparison of Spo 2 to Pao 2 based markers of lung disease severityfor children with acute lung injury. Crit Care Med. 2012;40(4):1309-16.
Sanchez Casado M, Quintana Diaz M, Palacios D, Hortiguela V, Marco Schulke C, Garcia J, et al. Relationship between the alveolar-arterial oxygen gradient and PaO(2)/FiO(2)-introducing PEEP into the model. Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2012;36(5):329-34.
Khemani RG, Thomas NJ, Venkatachalam V, Scimeme JP, Berutti T, Schneider JB, et al. Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury. Crit Care Med. 2012;40(4):1309-16.
Cawcutt KA, Peters SG. Severe Sepsis and Septic Shock: Clinical Overview and Update on Management. Mayo Clinic proceedings. 2014;89(11):1572-8.
Schmidt MF, Gernand J, Kakarala R. The use of the pulse oximetric saturation to fraction of inspired oxygen ratio in an automated acute respiratory distress syndrome screening tool. J Crit Care. 2015 Jun;30(3):486-90.