2018, Number 3
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Rev Cubana Invest Bioméd 2018; 37 (3)
ZIKA infection in pregnant women in a Hospital in Chiapas, Mexico
Cortes-Vidal S, Vidal-López DG, De Fuentes-Vicente JA, Moreno-Rodríguez A, Velázquez-Gómez M
Language: Spanish
References: 19
Page: 1-9
PDF size: 76.00 Kb.
ABSTRACT
Introduction: The Zika virus belongs to the Flaviviridae family, is spherical in
appearance and although the reservoir is not known, monkeys and some rodents are
suspected. This virus traditionally circulated only in cycles or African areas and in
parts of Southeast Asia and before 2007 only 14 human cases were known. In the
last decade, its expansion has been considerable in diverse regions causing epidemic
outbreaks as in America, where it is speculated that it is most likely to become an
endemic disease.
Objective: To document the signs and symptoms of a group of pregnant women
infected with the Zika virus.
Methods: We studied the medical records of 49 patients admitted during the period
April 2016-April 2017 in a hospital located in the southeast region of Mexico. The
infection was corroborated by Polymerase in real time and the signs and symptoms
were recorded taking into account the trimester of pregnancy. The relationship of the
clinical picture with the quarter was evaluated with the Chi-square test.
Results: The records indicated characteristic signs and symptoms such as fever,
headache, rash and pruritus. Others are documented less frequently, a zygote
detachment, a spontaneous abortion and a newborn with hearing loss. It was not
possible to establish a relationship between symptoms and signs with the trimester of
pregnancy (p = 0.8922).
Conclusions: Zika virus infection in pregnant women can lead to problems in the
proper development of the fetus. In addition, nonspecific symptoms could hinder their
timely diagnosis.
REFERENCES
Maguiña C, Galán-Rodas E. El virus Zika: una revisión de literatura. Acta Médica Peruana. 2016;33(1):35-41.
Hayes E. Zika Virus Outside Africa. Emerging Infectious Disease. 2009;15(9):1347-50.
Pacheco F, Mackarenna G, Olivares R, Luppi M, Gaete G. Virus Zika. Epidemiología, manifestaciones clínicas y prevención.
Loredo Abdala A, Figueroa Becerril Z, Vargas Flores J, Perea Martínez A, Arredondo García J, Casas Muñoz, et al. Zika: ¿catástrofe biológica mundial? Acta Pediátrica de México. 2016;37(6):341-48.
Hernández Rojas P. Infección por virus Zika en el embarazo. Salus. 2016;20(1):52-7.
Nuñez E, Vásques M, Beltrán Luque B, Padgett D. Virus Zika en Centroamérica y sus complicaciones. Acta Médica Peruana. 2016;33(1):42-9.
Sierra M, Duarte Pineda A, Matamoros M. Vulnerabilidad del Continente Americano a enfermedades emergentes y re-emergentes: el ejemplo del Zika. Revista de Ciencias Forenses de Honduras. 2016;1(1):22-46.
Hortal M. Enfermedades infecciosas emergentes y reemergentes: información actualizada. Revista Médica del Uruguay. 2016;(32(1):52-8.
Coronell Rodríguez W, Arteta Acosta C, Suárez Fuentes A, Burgos Rolon C, Rubio Sotomayor T, Sarmiento Gutiérrez M, et al. Infección por virus del Zika en el embarazo, impacto fetal y neonatal. Revista Chilena de Infectología. 2016;33(6):665-3.
Foy B, Kobylinski J, Chilson F, Blitvich A, Travassos A. Probable non-vector-borne transmission of Zika virus, Colorado, USA. Emerging Infectious Diseases. 2011;17(5):880-82.
World Health Organization (WHO). WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations. Feb 1, 2016.
Martínez Fernández L, Torrado Navarro P. Fiebre Chikungunya. Revista Cubana de Medicina. 2015;54(1):74-96.
Wladimir J, Briones Gavilanes J. Algunas consideraciones generales sobre la enfermedad por el virus Zika. Dominio de las Ciencias. 2016;2:29-46.
Mor G. Placental inflamatory response to Zika virus may affect fetal brain development. American Journal of Reproductive Immunology. 2016;75(4):421-2.
Mlakar J, Korva M, Tul N, Popovic M, Mraz J, Kolenc M, et al. Zika virus associated with microcephaly. The New England Journal of Medicine. 2016;374:951-8.
Mesci P, Macia A, Moore S, Shiryaev S, Pinto A, Huang C, et al. Blocking Zika virus vertical transmission. Scientific Reports. 2018;8:1-13.
Shi Y, Li S, Sun L, Zhang J, Pan N, Wang Q, et al. Vertical transmission of the Zika virus cause neurological disordersin mouse offspring. Scientific Reports. 2018;354(8):1-14.
Bayer A, Lennemann N, Ouyang Y, Bramley J, Morosky S, Marques E, et al. Type III interferons produced by human placental trophoblasts confer protection against Zika virus infection. Cells Host & Microbes. 2016;19(5):705-12.
García Solís E. Zika ¿Un dilema bioético? Revista Latinoamericana de Patología Clínica. 2016;63(2):76-8.