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Federación Mexicana de Ginecología y Obstetricia, A.C.

2019, Number 08

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Ginecol Obstet Mex 2019; 87 (08)

Correlation of the serum levels of Anti-müllerian Hormone and woman age with the rate of ovular recovery and Pregnancy

Mendoza-Celaya JA, Kably-Ambe A, Carballo-Mondragón E, Roque-Sánchez AM, Benítez-Castro KL

Language: Spanish
References: 24
Page: 535-542
PDF size: 430.32 Kb.


ABSTRACT

Objective: To evaluate the outcomes in oocyte retrieval and the pregnancy rate in patients under in vitro fertilization protocol according to anti-Müllerian hormone concentrations and the age of the woman.
Materials and methods: Retrospective, cross-sectional, comparative and observational study carried out in patients undergoing in vitro fertilization treatment in a private assisted reproduction center (January 2013- January 2018). The population was divided into group 1 (lower concentrations of 1 ng / mL of antimülleriana hormone) and group B (concentrations higher than 1 ng / mL of antimülleriana hormone) to determine the association between the age and the antimülleriana hormone concentrations and the answer to the amount of recovered oocytes and pregnancy rate; these groups were subdivided by age (≤ 29, 30-34, 35-39 and ≥ 40 years).
Results: We studied 282 patients, of which 35 were eliminated due to incomplete records; there were 247; 93 in group 1 and 154 in group 2. In group 1, 4.61 vs 7.9 oocytes were recovered (p ‹0.001). In patients younger than 29 years old with antimüllerian hormone concentrations lower than 1 ng / mL, the average number of oocytes retrieved was higher: 7.8 oocytes versus the other age groups with less than 1 ng / mL. The pregnancy rate in patients with antimüllerian hormone concentrations greater than 1 ng / mL was higher in the age groups under 29 years and 30 to 34 years (p ‹0.01).
Conclusions: Regardless of age, when antimüllerian hormone concentrations are greater than 1 ng/mL, more oocytes are recovered than in those less than that concentration. Patients younger than 35 years old with antimüllerian hormone concentrations lower than 1 ng/mL have a higher pregnancy rate than those less than 1 ng/mL. When the age of the woman is over 35 years old, anti-Müllerian hormone concentrations do not influence pregnancy rates.


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