2019, Number 1
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CIU Cardiac Image Updated 2019; 1 (1)
Radial deformation and left ventricle rotation of the base are mechanisms associated with the severity of primary mitral regurgitation
Ávila VN, Fritche-Salazar JF, Parra ONA, Herrera BH
Language: English
References: 13
Page: 8-14
PDF size: 162.64 Kb.
ABSTRACT
Introduction: The rotational mechanics of the left ventricle (LV) are part of the function of the mitral annulus; the loss of this mechanism has been associated with the severity of mitral regurgitation (MR). Our objective was to evaluate whether the rotation of the LV base is a mechanism associated with the severity of MR.
Methods: A cross-sectional analytical study was designed. Patients older than 18 years old with non-ischemic MR were included. A healthy control group was analized.
Results: Ninety-one participants were included, 57 cases and 34 controls. The patients with MR had worse ventricular strain (longitudinal, radial and circumferential). The case group were divided by severity of regurgitation; longitudinal strain had a progressive decrease from mild to severe MR (-19% [95%CI -22%-15%] and -14% [95%CI -17%-6%]) respectively (p‹0.033). Twist in patients with mild MR was 16
o (13.6-19.4), which decreases to 10.8
o (7.3-17.3) in severe MR (p‹0.034), torsion shows a similar pattern with a value of 2.05
o/cm, in the mild MR, and that decreases to 1.1
o/cm in severe MR (p‹0.038). Multivariate analysis shown that the independents mechanisms associated with severity of MR were: radial strain (OR:1.08, 95%CI:1.03-1.13, p‹0.006), and basal rotation [OR:1.14 95% CI 1.07-1.26, p‹0.02].
Conclusion: In MR of non-ischemic etiology, poor rotation of the base and poor radial strain were associated with MR severity.
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