2018, Number 2
<< Back Next >>
Ortho-tips 2018; 14 (2)
Periprosthetic knee infection in patients with nasal Staphylococcus aureus
Males-Hoyos J, Pérez-Atanasio JM, Lagunas-Sánchez CE, Farías BVA, Nava TTM
Language: Spanish
References: 16
Page: 53-59
PDF size: 164.62 Kb.
ABSTRACT
Background: Periprosthetic joint infection (PJI) is a common complication due to the increase of senile population and their comorbidities and therefore the increase of joint replacement procedures. The status of the
Staphylococcus aureus carrier increases the incidence and the risk of (PJI).
Methods: Prospective analytical cohort study, carried in patients that were undergoing into a primary total knee arthroplasty, between January and April of 2018. A nasal swab culture was performed before the surgical event in order to detect carrier patients. Patients were monitoring during three months to collect information to know the incidence PJI in nasal carriers of SA and other related risk factors.
Results: We studied 73 patients. The early PJI global incidence was 5.5%. The incidence PJI in nasal carriers of SA was 12.3%. The incidence of PJI carrier patients was 22.2%, the relation statistically significant was (p: 0.01) and relative risk of (RR): 8.81 IC (95%): 1.07-73 if it is PJI carrier.
Conclusions: Carriers of SA has a higher incidence of early PJI, there is a relation statistically significant among being a carrier and present PJI.
REFERENCES
Della-Valle C, Parvizi J, Bauer TW, Dicesare PE, Evans RP, Segreti J, et al. Diagnosis of periprosthetic joint infections of the hip and knee. J Am Acad Orthop Surg. 2010; 18 (12): 760-770.
Tande AJ, Patel R. Prosthetic joint infection. Clin Microbiol Rev. 2014; 27 (2): 302-345.
Kurtz SM, Ong KL, Schmier J, Mowat F, Saleh K, Dybvik E, et al. Future clinical and economic impact of revision total hip and knee arthroplasty. J Bone Joint Surg Am. 2007; 89 Suppl 3: 144-151.
Bozic KJ, Kurtz SM, Lau E, Ong K, Vail TP, Berry DJ. The epidemiology of revision total hip arthroplasty in the United States. J Bone Joint Surg Am. 2009; 91 (1): 128-133.
Adeli B, Parvizi J. Strategies for the prevention of periprosthetic joint infection. J Bone Joint Surg Br. 2012; 94 (11 Suppl A): 42-46.
Zimmerli W, Trampuz A, Ochsner PE. Prosthetic-joint infections. N Engl J Med. 2004; 351 (16): 1645-1654.
Sendi P, Zimmerli W. Challenges in periprosthetic knee-joint infection. Int J Artif Organs. 2011; 34 (9): 947-956.
Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007; 89 (4): 780-785.
Kurtz SM, Lau E, Schmier J, Ong KL, Zhao K, Parvizi J. Infection burden for hip and knee arthroplasty in the United States. J Arthroplasty. 2008; 23 (7): 984-991.
Peel TN, Cheng AC, Buising KL, Choong PF. Microbiological aetiology, epidemiology, and clinical profile of prosthetic joint infections: are current antibiotic prophylaxis guidelines effective? Antimicrob Agents Chemother. 2012; 56 (5): 2386-2391.
Skaar DD, O’Connor H, Hodges JS, Michalowicz BS. Dental procedures and subsequent prosthetic joint infections: findings from the Medicare Current Beneficiary Survey. J Am Dent Assoc. 2011; 142 (12): 1343-1351.
Skråmm I, Fossum Moen AE, Årøen A, Bukholm G. Surgical site infections in orthopaedic surgery demonstrate clones similar to those in orthopaedic Staphylococcus aureus nasal carriers. J Bone Joint Surg Am. 2014; 96 (11): 882-888.
van Rijen MM, Bode LG, Baak DA, Kluytmans JA, Vos MC. Reduced costs for Staphylococcus aureus carriers treated prophylactically with mupirocin and chlorhexidine in cardiothoracic and orthopaedic surgery. PLoS One. 2012; 7 (8): e43065.
Weiser MC, Moucha CS. The current state of screening and decolonization for the prevention of Staphylococcus aureus surgical site infection after total hip and knee arthroplasty. J Bone Joint Surg Am. 2015; 97 (17): 1449-1458.
Kalmeijer MD, Coertjens H, van Nieuwland-Bollen PM, Bogaers-Hofman D, de Baere GA, Stuurman A, et al. Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study. Clin Infect Dis. 2002; 35 (4): 353-358.
Hidron AI, Kourbatova EV, Halvosa JS, Terrell BJ, McDougal LK, Tenover FC, et al. Risk factors for colonization with methicillin-resistant Staphylococcus aureus (MRSA) in patients admitted to an urban hospital: emergence of community-associated MRSA nasal carriage. Clin Infect Dis. 2005; 41 (2): 159-166.