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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2018, Number 4

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An Med Asoc Med Hosp ABC 2018; 63 (4)

Carbon monoxide-induced cardiomyopathy

Fuentes GAJ, Gómez MC, Aguirre SJS, Martínez DB

Language: Spanish
References: 15
Page: 288-292
PDF size: 231.70 Kb.


ABSTRACT

Carbon monoxide intoxication is the main accidental death cause associated with a toxic substance; its high incidence is probably secondary to the physicochemical characteristics of the molecule, that make it go unnoticed. When there is an exposition to high levels of carbon monoxide during enough time, target organ damage appears, the myocardium being one of the most susceptible tissues, and that can precipitate irreversible ischemic damage. Carbon monoxide-induced cardiomyopathy is a subtype of stress injury related to a different physiopathology and clinical spectrum that shares characteristics with takotsubo cardiomyopathy, but requires a distinct treatment. A clinical case of carbon monoxide intoxication is presented, in a female patient with high serum levels of carboxyhemoglobin leading to the development of cardiomyopathy; we highlight the diagnostic assessment, follow-up and hemodynamic support in the intensive care unit during the initial phases of the disease. The objective was to review the current information reported on carbon monoxide-induced cardiomyopathy, which is a poorly known pathological condition because of its low frequency, and with scarce published cases. Despite the lack of a specific treatment, hyperbaric oxygen, inotropic drugs, ventricular assist devices and extracorporeal membrane therapies are therapeutic options that have been used in this pathology.


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