2018, Number 4
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Rev Hematol Mex 2018; 19 (4)
Generalities about lymphomas
Pérez-Zúñiga JM, Aguilar-Andrade C, Álvarez-Vera JL, Augusto-Pacheco M, Báez-Islas PE, Bates-Martín RA, Cervantes-Sánchez I, Espitia-Ríos ME, Estrada-Domínguez P, Jiménez-Alvarado R, Fermín-Caminero DJ, García-Camacho AS, Gómez-Rosas P, Grimaldo-Gómez FA, Guzmán-Mera P, Herrera-Olivares W, Martínez-Ramírez MA, Medina-Meza C, Mena-Zepeda V, Montoya-Jiménez L, Morales-Adrián JJ, Morales-Hernández AE, Mujica-Martínez A, Palma-Moreno OG, Reyes-Brena G, Reynoso-Pérez AO, Salazar-Ramírez Ó, Hernández-Ruiz E, Paredes-Lozano EP, Alvarado-Ibarra M
Language: Spanish
References: 19
Page: 174-188
PDF size: 500.24 Kb.
ABSTRACT
Nowadays, cancer have increased; non-Hodgkin lymphomas in Mexico represent the
second cause of hematological malignancies, in addition, there are methods of staging
the disease, risk and an approach to gene expression profiles by immunohistochemistry
that have important implications in diagnosis, prognosis and treatment. Over time,
the diagnostic instruments, equipment and techniques have been perfected, which
allows the optimization of the results to establish the basic measures to subclassify the
lymphomas by histological strain, phenotype B or T, degree of maturation, replication
index as well as molecular characteristics and even differentiation algorithms. Once the
variety and subtype of lymphoma are defined, there are other issues for the clinician,
among which are the sites involved and with these sites, the optimal classification
system, whatever it is, which allows optimizing the final results and predicting the
possible outcomes in survival is this group of patients. The target of this document
is to summarize the general characteristics to be considered in patients with non-
Hodgkin lymphoma at the beginning of treatment; however, it should be remembered
that advances in this medical area may generate controversies with this review and
must dominate clinical reasoning and the medicine based on evidence in favor of the
clinical benefit of the patients.
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