Obregón-Corona A, Silva-Arista CG, Gutiérrez-Gutiérrez A, Manrique-Carmona LP

Language: Spanish
References: 16
Page: 258-262
PDF size: 204.35 Kb.

ABSTRACT

Introduction: Electroconvulsive therapy (ECT) is a useful treatment in several mental illnesses, the administration of anesthesia is essential in order to givepatientsquality conditions; knowing drugs pharmacokinetics and pharmacodynamics facilitate their choice; cerebral oximetry is a non-invasive method that shows how oxygen balance is found at brain regional level; sodium thiopental has been widely used in anesthesia, it has properties that allows convulsive response as wanted in ECT. Propanidido is an pharmacological alternative that guarantees quick onset and recovery. Material and methods: We included 59 adults who received ECT for different psychiatric diagnoses. Two groups were randomly assigned; one received sodium thiopental (group T) and the other propanidide (group P), frontal cerebral oximetry was measured at different moments: basal, induction, during the seizure, at 5 and 10 minutes of recovery. Results: It was found similar behavior of cerebral oximetry in both groups, except at the time of the seizure that was higher in group T: 67.7 ± 11.6 versus 59.9 ± 6.23 (‹ 0.01). Conclusion: Both sodium thiopental and propanidide behave similarly in terms of cerebral oximetry, the increase during seizure in group T may be due to the latency period to ensure discharge quality.

REFERENCES

1. Singh A, Kar SK. How electroconvulsive therapy works?: understanding the neurobiological mechanisms. Clin Psychopharmacol Neurosci. 2017;15:210-221.

2. Deiner S, Frost EA. Electroconvulsive therapy and anesthesia. Int Anesthesiol Clin. 2009;47:81-92.

3. Yu Y, Zhang K, Zhang L, Zong H, Meng L, Han R. Cerebral near-infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults. Cochrane Database Syst Rev. 2018;1:CD010947.

4. Watzman HM, Kurth CD, Montenegro LM, Rome J, Steven JM, Nicolson SC. Arterial and venous contributions to near-infrared cerebral oximetry. Anesthesiology. 2000;93:947-953.

5. Hirano J, Takamiya A, Yamagata B, Hotta S, Miyasaka Y, Pu S, et al. Frontal and temporal cortical functional recovery after electroconvulsive therapy for depression: A longitudinal functional near-infrared spectroscopy study. J Psychiatr Res. 2017;91:26-35.

6. Tanious MK, Beutler SS, Kaye AD, Urman RD. New hypnotic drug development and pharmacologic considerations for clinical anesthesia. Anesthesiol Clin. 2017;35:e95-e113.

7. Katre AM, Pandya SH. Comparative evaluation of propanidid with thiopentone as an anaesthetic agent for electro-convulsive therapy. J Postgrad Med. 1980;26:171-177.

8. Salehi B, Mohammadbeigi A, Kamali AR, Taheri-Nejad MR, Moshiri I. Impact comparison of ketamine and sodium thiopental on anesthesia during electroconvulsive therapy in major depression patients with drug-resistant; a double-blind randomized clinical trial. Ann Card Anaesth. 2015;18:486-490.

9. Barraza-Espinoza V. Propanidido en México: mitos y realidades. Rev Mex Anest. 2017;40:79-89.

10. Abbott CC, Gallegos P, Rediske N, Lemke NT, Quinn DK. A review of longitudinal electroconvulsive therapy: neuroimaging investigations. J Geriatr Psychiatry Neurol. 2014;27:33-46.

11. Bolwig TG. Neuroimaging and electroconvulsive therapy: a review. J ECT. 2014;30:138-142.

12. Rasmussen P, Andersson JE, Koch P, Secher NH, Quistorff B. Glycopyrrolate prevents extreme bradycardia and cerebral deoxygenation during electroconvulsive therapy. J ECT. 2007;23:147-152.

13. Saito S, Yoshikawa D, Nishihara F, Morita T, Kitani Y, Amaya T, et al. The cerebral hemodynamic response to electrically induced seizures in man. Brain Res. 1995;673:93-100.

14. Canbek O, Ipekcıoglu D, Menges OO, Atagun MI, Karamustafalıoglu N, Cetinkaya OZ, et al. Comparison of propofol, etomidate, and thiopental in anesthesia for electroconvulsive therapy: a randomized, double-blind clinical trial. J ECT. 2015;31:91-97.

15. Lyndon W, Wilson C. Anesthesia for electroconvulsive therapy--time for a review? Brain Stimul. 2015;8:985-986.

16. Fujita Y, Takebayashi M, Hisaoka K, Tsuchioka M, Morinobu S, Yamawaki S. Asymmetric alternation of the hemodynamic response at the prefrontal cortex in patients with schizophrenia during electroconvulsive therapy: a near-infrared spectroscopy study. Brain Res. 2011;1410:132-140.