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2018, Number 1

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Residente 2018; 13 (1)

Artritis reumatoide y riesgo de fracturas osteoporóticas

Vizcaíno-Cortés ZG, Enríquez-Luna A, Esparza-Guerrero Y, Farías-Cuevas KP, Reyes-Reyes HA, Ramírez-Villafaña M, Castro-Jiménez A, Morales-Lira RI, Sánchez-Flores SE, Díaz-Pérez SA, González-López LC, Saldaña-Cruz AM

Language: Spanish
References: 37
Page: 4-11
PDF size: 247.83 Kb.


ABSTRACT

Rheumatoid arthritis (RA) is a chronic autoimmune disease, of multifactorial etiology with the presence of different autoantibodies, characterized by symmetrical polyarticular inflammation of more than three groups of joints including small and large, causes destruction in the articular cartilage with increased risk of osteoporosis and osteoporotic fractures. Osteoporosis is a decrease in bone mass, with increased bone resorption and decreased formation, leading to the fragility of microarchitectural bone. Osteoporotic fractures are 1.5 times more common in RA patients compared to controls without the disease. Its pathogenesis is multifactorial with genetic and epidemiological factors related to the disease and treatments, mainly the indiscriminate use of glucocorticoids, among others. In relation to vertebral fractures, these are observed two to three times more often than in the general population. This review addresses the epidemiological, diagnostic and treatment aspects of osteoporotic fractures.


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