2018, Number 2
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Gac Med Mex 2018; 154 (2)
Impacto de la revascularización y factores asociados en el salvamento de la extremidad en pacientes con pie diabético
Hinojosa CA, Boyer-Duck E, Anaya-Ayala JE, Núñez-Salgado AE, Laparra-Escareno H, Lizola R
Language: Spanish
References: 24
Page: 190-197
PDF size: 210.91 Kb.
ABSTRACT
Introduction: Diabetic foot is a common cause of hospitalization.
Objective: To examine the impact of revascularization on
lower limb salvage.
Method: Retrospective study of diabetic patients with foot ulcers. The extent of tissue loss was assessed
according to the PEDIS and Wagner classifications, and revascularization indications and techniques were evaluated. Factors
involved with major amputation and limb salvage were assessed with Fisher’s and chi-square tests.
Results: A total of 307 patients
with a mean age of 61 years were included in the study; 198 (64%) were males; 53 (17%) underwent limb revascularization,
26 (8%) with endovascular techniques and 27 (9%) with open surgery; 27 belonged to PEDIS grade 3 (51%) and
21 (41%) to Wagner’s classification grade 4; 52% of revascularized patients required major amputation versus 25% of those
without revascularization. Comorbidities, demographic variables, complications and mortality showed no differences when
patients who required major amputation were compared with those who didn’t.
Conclusion: Despite revascularization, the limb
was preserved in less than 50% of patients. Early referral to vascular surgery and appropriate patient-selection criteria might
increase limb salvage.
REFERENCES
Richard JL, Schuldiner S. Epidemiology of diabetic foot problems. Rev Med Int. 2008;29(Suppl 2):S222-S230.
Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005;293(2):217-228.
Driver VR, Fabbi M, Lavery LA, Gibbons G. The cost of diabetic foot, the economic case for the limb salvage team. J Vasc Surg. 2010;52(3 Suppl):17S-22S.
Lavery LA, Armstrong DG, Wunderlich RP, Mohler MJ, Wendel CS, Lipsky BA. Risk factors for foot infections in individuals with diabetes. Diabetes Care. 2006;29(6):1288-1293.
Armstrong DG, Mills JL. Toward a change in syntax in diabetic foot care prevention, equals remission. J Am Podiatr Med Assoc. 2013;103(2):161-162.
Armstrong DG, Wrobel J, Robbins JM. Guest editorial: are diabetes related wounds and amputations worse than cancer? Int Wound J. 2007;4(4):286-287.
Apelqvist J, Bakker K, Van-Houtum WH, Nabuurs-Franssen MH, Schaper NC. International consensus and practical guidelines on the management and the prevention of the diabetic foot. International Working Group on the Diabetic Foot. Diabetes Metab Res Rev. 2000;16(Suppl 1):S84-92.
Schaper NC, Apelvist J, Bakker K. Reducing lower leg amputation in diabetes: a challenge for patients healthcare providers and healthcare system. Diabetologia. 2012;55(7):1869-1872.
Armstrong DG, Lavery LA, Harkless LB. Validation of a diabetic wound classification system. The contributions of depth, infection, and ischemia to risk of amputation. Diabetes Care. 1998;21(5):855-859
Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg. 2007;45(1 Suppl):S5-S67.
Eslami MH, Zayaruzny M, Fitzgerald GA. The adverse effects of race, insurance status, and low income on the rate of amputation in patients presenting with lower extremity ischemia. J Vasc Surg. 2007; 45(1):55-59.
Alexandrescu V, Hubermont G, Philips Y, Guillaumie B, Ngongang C, Coessens V, et al. Combined primary subintimal and endoluminal angioplasty for ischaemic inferior limb ulcers in diabetic patients: 5-year practice in multidisciplinary diabetic foot service. Eur J Vasc Endovasc Surg. 2009;37(4):448-456.
Castro G, Liceaga G, Arrioja A, Calleja JM, Espejel A, Flores J, et al. Guía clínica basada en evidencia para el manejo del pie diabético. Med Int Mex. 2009;25(6):481-526.
Schaper NC. Diabetic foot ulcer classification system for research purposes: a progress report on criteria for including patients in research studies. Diabetes Metab Res Rev. 2004;20(Suppl 1):S90-S95.
Bell PRF, Charlesworthd D, DePalma RG, Eastcostt HHG, Eklof B, Jamieson CW, et al. The definition of critical ischemia of a limb. Working Party of the International Vascular Symposium. Br J Surg. 1982; 69(Suppl 1):S2.
Apelquvist J, Elgzyri T, Larrson J, Löndahl M, Nyberg P, Thörne J. Factors related to outcome of neuroischemic/ischemic foot ulcer in diabetic patients. J Vasc Surg. 2011;53(6):1582-1588.
Wagner FW. The dysvascular foot: a system for diagnosis and treatment. Foot Ankle. 1981;2(2):64-122.
Mills JL Sr, Conte MS, Armstrong DG, Pomposelli FB, Schanzer A, Sidawy AN, et al. The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: risk stratification based on wound, ischemia, and foot infection (WIfI). J Vasc Surg. 2014;59(1):220- 234.e1-2.
Zhan LX, Branco BC, Armstrong DG, Mills JL. The Society for Vascular Surgery lower extremity threatened limb classification system based on Wound, Ischemia, and foot Infection (WIfI) correlates with risk of major amputation and time to wound healing. J Vasc Surg. 2015;61(4):939-944.
Elgzyri T, Larsson J, Nyberg P, Thörne J, Eriksson KF, Apelqvist J. Early revascularization after admittance to a diabetic foot center affects the healing probability of ischemic foot ulcer in patients with diabetes. See comment in PubMed Commons belowEur J Vasc Endovasc Surg. 2014;48(4):440-446.
Cabeza-De-Vaca FG, Macias AE, Ramirez WA, Munoz JM, Alvarez JA, Mosqueda JL, et al. Salvaging diabetic foot through debridement, pressure alleviation, metabolic control, and antibiotics. Wound Repair Regen. 2010;18(6) 567-571.
Lepäntalo M, Apelqvist J, Setacci C, Ricco JB, De-Donato G, Becker F, et al. Chapter V: diabetic foot. Eur J Vasc Endovasc Surg. 2011;42(Suppl. 2):S60-S74.
Hinchliffe RJ, Andros G, Apelvist J, Bakker K, Friederich S, Lammer J, et al. A systemic review of the effectiveness of revascularization of the ulcerated foot in patients with diabetes and peripheral arterial disease. Diabetes Metab Res Rev. 2012;28(Suppl 1):179-217.
Faglia E, Clerici G, Caminiti M, Quaranteiello A, Gino M, Morabito A. The role of early surgical debridment and revascularization in patients with diabetes and deep foot space abscess: retrospective review of 106 patients with diabetes. J Foot Ankle Surg. 2006;45(4):220-226.