Mercado AL, González MRJ, Martínez RMA, Iglesias LJ, Bernárdez ZI, Braverman BA

Language: Spanish
References: 21
Page: 31-37
PDF size: 244.40 Kb.

ABSTRACT

Background: Preterm’ growth pattern is based on a fetal model; if this pattern was ideal, newborns would maintain a lineal growth. Nevertheless, postnatal growth is usually modified by postnatal factors. Objective: To evaluate the growth pattern in preterm infants, and to estimate associations between neonatal features and medical treatment with longitudinal growth rate and size at discharge. Material and methods: Observational, descriptive, retrospective, longitudinal study. We included 83 newborns (28-34 weeks of gestational age). We present descriptive statistics to analyze neonatal features and medical treatment. The longitudinal growth rate was defined as the relation between the weekly size increment and inpatient weeks. We adjusted a multivariate linear regression model to estimate the association between neonatal features and medical treatment with longitudinal growth rate. Results: 12% were discharged with a low height. The longitudinal growth rate was 0.86 cm/week; for head circumference: 0.47 cm/week. The longitudinal growth rate was increased by (cm/week) sepsis (β = 0.46 [IC_95% 0.06,0.86]) and parenteral nutrition (β = 0.30 [IC_95% 0.00,0.60]); it was decreased by (cm/week) fasting (β = 0.43 [IC_95% -0.76,-0.11]), each week of gestation (β = 0.10; [IC_95% -0.19,-0.01]), aminergic support (β = 0.54 [IC_95% -0.98,-0.1]), intraventricular hemorrhage (β = 0.70 [IC_95% -1.25,-0.14]), each unit of Miller Index (β= 2.67 [IC_95% -4.45,-0.89]). Conclusions: Most cases were classified as low birth height; they had growth retardation periods and nevertheless they caught-up on the first weeks. We associated increment of longitudinal growth rate with sepsis and parenteral nutrition; and decrease with fasting, aminergic support, intraventricular hemorrhage, older gestational age and higher Miller Index.

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