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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2005, Number 4

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An Med Asoc Med Hosp ABC 2005; 50 (4)

Postoperative analgesia evaluation with intra-articular dexmedetomidine and ropivacaine in patients with knee arthroscopic surgery

García MT, Guadarrama QF, Díaz HA, Reyes ERE, Gutiérrez GA, Covarrubias VJA

Language: Spanish
References: 17
Page: 156-162
PDF size: 73.79 Kb.


ABSTRACT

One of the most common complication in arthroscopic ambulatory surgery is pain. Anaesthetics like lidocaine, bupivacaine and ropivacaine have been used by intraarticular path. Alpha 2 adrenergic agonists combined with local anaesthetics provide better analgesia based on increasing time of action, reducing opioid requirements and diminishing hemodynamic response. Design: Controlled, prospective, randomized, double blind study. Adult patients. ASA I-II underwent arthroscopic surgery. At the end of the surgery, ropivacaine and dexmedetomidine were administered intraarticular. Patients were divided into three groups: Group I: ropivacaine 1.5 mg/kg + dexmedetomidine 0.5 μg/kg. Group II: ropivacaine 1.5 mg/kg and group III: dexmedetomidine 0.5 μg/kg. Basically, four points in particular were evaluated: postoperative analgesia, pain release requirements, hemodynamic response and adverse effects. Results: 60 patients, 20 patients per group. In relation to hemodynamics, significant differences were given by patients in group II. Relating to analgesia, there were significant differences in all evaluation periods comparing group I versus II and III. No differences were found between groups II and III at 12 and 24 h. Adverse effects: The incidence of nausea was 10% for group 1, 0 for group II and 15% for group III. Conclusion: Combining ropivacaine 1.5 mg/kg and dexmedetomidine 0.5 μg/kg via intraarticularly, provides effective postoperative analgesia for a longer time in patients that underwent knee arthroscopic surgery.


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