2017, Number 4
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Rev Mex Anest 2017; 40 (4)
New oral anticoagulants and neuroaxial anesthesia
Pingarrón-Ríos RA, Castorena-Arellano GA, Calderón-Vidal M
Language: Spanish
References: 26
Page: 288-294
PDF size: 193.03 Kb.
ABSTRACT
Neuroaxial regional anesthesia is an effective and safe method to provide adequate anesthesia and analgesia in the postoperative period. Reasons to receive neuroaxial anesthesia are diverse, but preoperative conditions, surgical trauma and prolonged postoperative rest, may produce a thromboembolic venous disease which constitutes the most frequent indication of anticoagulation in the perioperative period. In hospital thromboprophylaxis, enoxaparin, a low molecular weight heparin or similar drugs are the most commonly used anticoagulants. However, in the last decade the so-called «new oral anticoagulants» (NOAC) are also available. These are: direct inhibitors of thrombin (such as dabigatran) and factor Xa inhibitors (rivaroxaban and apixaban), with some advantages over low molecular weight heparins. The anesthesiologist should be aware of evidence-based recommendations for the proper management of the new oral anticoagulants in these patients.
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